Central adiposity at diagnosis may reduce prostate cancer-specific mortality in African-Caribbean men with prostate cancer: 10-year follow-up of participants in a case–control study

Post-Diagnostic Dietary and Lifestyle Factors and Prostate Cancer Recurrence, Progression, and Mortality

“…HR per 5-unit : 1.07; CI; 1.02, 1.12; p = 0.01) [24,27,34]. The two others observed no associations with BMI, waist circumference, or waist-to-hip ratio [23,29]. There were numerous older studies that reported similarly null findings between BMI and ACM among men with PC ( Table 2).…”

“…Seven studies published between 2015 and 2020 examined BMI and PCSM [23,24,26,[29][30][31]34]. Only one-a study of 1442 men treated with intensity modulated radiation therapy for localized disease, and therefore lacking pathologic measures of disease severity-observed an association (HR continuous : 1.15; CI: 1.07, 1.23; p < 0.001) [34].…”

“…Three additional studies published before 2015 also reported a positive association, only one of which controlled for pathologic metrics [57][58][59]. The two studies that considered waist circumference and waist-to-hip ratio found no association [23,29].…”

“…Five studies published between 2015 and 2020 examined BMI and ACM with mixed results [23,24,27,29,34]. Three of these reported a higher risk associated with higher BMI (HR ≥ 35 vs 18.5-25 : 1.70 (1.12, 2.60), p trend = 0.001.…”

“…An additional seven dichotomized race as White/Caucasian vs other (all ≥ 92% White) [4,5,12,18,24,31,39]. Only six included ≥ 10% AA/B/African-Caribbean men [23,26,28,30,33,44].…”