Central Auditory Damage Induced by Solvent Exposure

Abstract

auditory processing auditory damage hearing solvent exposure speech discrimination

Adolescent toluene exposure produces enduring social and cognitive deficits in mice: An animal model of solvent-induced psychosis

“…Although toluene abuse does not cause active demyelination (Aydin et al 2003), white matter abnormality and neuronal loss might be related to adolescent toluene-induced behavioural abnormalities in adults. Moreover, organic solvents also have detrimental effects on olfactory (Gelazonia et al 2006) and auditory systems (Lataye et al 1999;Fuente and McPherson 2007), which may be also related to the long-lasting behavioural dysfunction, including social withdrawal and recognition memory impairment.…”

Random Gap Detection Test (RGDT) performance of individuals with central auditory processing disorders from 5 to 25 years of age

“…RGDT was also used in workers exposed to solvent [10], in individuals with auditory neuropathy [11] or CAPD [12,13]. Results revealed longer gap detection thresholds for the experimental group when compared to the gap for the control group [10][11][12].…”

Auditory system dysfunction in Brazilian gasoline station workers

“…The P300 auditory responses for gasoline station workers in this study were not significantly different than non-exposed study participants. Considering that many studies have used behavioural auditory processing tests and have found evidence for CAPD in workers exposed to solvents (Fuente and McPherson 2007a;Fuente, McPherson, and Hickson 2011;Fuente, McPherson, and Hickson 2013), P300 assessments may not be sensitive for the detection of effects of gasoline vapours on the auditory system. Thus, it is suggested that in further studies with gasoline station workers, behavioural central auditory processing tests be used.…”

“…Gasoline components such as ethylbenzene, toluene and xylene can damage the peripheral and/or the central auditory system (for a review see Johnson and Morata 2010). Central auditory disorders have been observed in workers who have normal hearing thresholds following exposure to toluene (Abbate et al 1993); solvents from a paint factory (Fuente and McPherson 2007a); mixture of organic solvents (xylene, toluene, methyl ethyl ketone) (Fuente and McPherson 2007b) and gasoline vapours .…”