Central Corneal Thickness Among Filipino Patients in an Ambulatory Eye Surgery Center Using Anterior Segment Optical Coherence Tomography

Abstract

Objective The purpose of the study was to determine the central corneal thickness (CCT) among Filipino patients that may contribute to different glaucoma diagnosis using the anterior segment optical coherence tomography in an ambulatory eye surgery center. Methods A single-center retrospective, cross-sectional study design including 1232 eyes of 641 patients of the Asian Eye Institute, Makati, Philippines from January 2019 to December 2019 who had their CCT measured with Visante anterior segment optical coherence tomography (AS-OCT). CCT was correlated with age, sex, presence of diabetes and/or hypertension, and glaucoma diagnosis. Results Among 641 patients who had their CCT measured by Visante AS-OCT, 723 eyes of 369 patients were included. Nearly half of the study population were normal or glaucoma suspects. The mean CCT among Filipino patients was 535.59 ± 34.06 µm. Ocular hypertensive patients had the thickest CCT, while normal tension glaucoma patients had the thinnest CCT. After adjusting for multiple variables, CCT had a direct relationship with the presence of diabetes, IOP level and the diagnosis of ocular hypertension, while inverse relationship with age. Most of the patients presenting with angle closure glaucoma were females aged 60 and above. Conclusion Visante AS-OCT is a non-contact and non-aerosol generating instrument allaying the fear of disease transmission from contact or aerosolization of tears. Our study confirms similar relationships of CCT with age, presence of diabetes, IOP level, and diagnosis of ocular hypertension or normal tension glaucoma among Filipino patients with the available literature from other ethnicities.

Comparison of Three Tonometers in Measuring Intraocular Pressure in Eyes That Underwent Myopic Laser in situ Keratomileusis and Photorefractive Keratectomy

“…Along with CCT, other parameters that may influence IOP readings were corneal curvature, tear film and biomechanical properties of the cornea. 10–12 Several authors have developed nomograms to correct GAT based on varying CCT. 13–16 However, the use of these nomograms remains controversial.…”