Central Corneal Thickness and Corneal Curvature in Pseudoexfoliation Syndrome With and Without Glaucoma

Özçura, Fatih; Aydın, Sayime; Dayanir, Volkan

doi:10.1097/ijg.0b013e3181f7afb8

Cited by 38 publications

(24 citation statements)

References 30 publications

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“…Ozcura et al showed that there was no significant change in CC in eyes with PXE compared with control eyes, [7] which is similar to the results obtained in the present study.…”

Section: Discussionsupporting

confidence: 82%

Chronomorphological and pressure changes in a sign of aging - pseudoexfoliation of the eye

Patil¹,

Herur²,

Brid³

et al. 2018

Natl J Physiol Pharm Pharmacol

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Background: Pseudoexfoliation (PXE) is an age-related disorder, a risk factor for glaucoma. The aim of this research was to study the chronomorphological and pressure changes in PXE of the eye. Aims and Objectives: To determine and to compare the anterior chamber depth (ACD), lens thickness (LT), axial length (AL), corneal curvature (CC), and intraocular pressure (IOP) in cases with PXE and in controls. Thence, predict the future onset of pseudoexfoliative glaucoma. Material and Methods: This was a case-control study, patients diagnosed to have PXE with the help of slit lamp, above 50 years were taken as cases and age-matched subjects as controls. Measurement of ACD, LT, and AL by A-scan; CC by Keratometer; and IOP by Schiotz tonometer of both cases and controls were performed. Results: Fourteen cases and seventeen controls were studied. A significant difference in mean IOP (P = 0.029) and AL (P = 0.001) between cases and controls was found. Conclusion: IOP and AL were significantly more in PXE as compared to controls. A significant increase in IOP and AL together may predict the future onset of PXE and hence, may help in early diagnosis of glaucoma and which may be missed in cases of PXE.

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“…Ozcura et al showed that there was no significant change in CC in eyes with PXE compared with control eyes, [7] which is similar to the results obtained in the present study.…”

Section: Discussionsupporting

confidence: 82%

Chronomorphological and pressure changes in a sign of aging - pseudoexfoliation of the eye

Patil¹,

Herur²,

Brid³

et al. 2018

Natl J Physiol Pharm Pharmacol

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“…The researchers represented that the corneal endothelial cell density and CCT were significantly lower in the PXS eyes than in the control eyes, but there were no significant differences in these factors between the PXS eyes in patients with and without glaucoma. Ozcura et al (27) reported that CCT was significantly thinner in eyes with PXS than in control eyes, but was not thinner in the eyes of those with pseudoexfoliative glaucoma.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Güneş¹,

Yigit²,

Tök³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Approved by the following research ethics committee: Süleyman Demirel University (# 72867572-050). ABSTRACT Purpose:To evaluate anterior segment parameters in patients with pseudoexfoliation syndrome (PXS) using Scheimpflug imaging. Methods: Forty-three PXS patients and 43 healthy control subjects were included in this cross-sectional study. All participants underwent a detailed ophthalmologic examination. Anterior segment parameters were measured using a Scheimpflug system. Results: Considering the PXS and control groups, the mean corneal thicknesses at the apex point (536 ± 31 and 560 ± 31 µm, respectively, p=0.001), at the center of the pupil (534 ± 31 and 558 ± 33 µm, respectively, p=0.001), and at the thinnest point (528 ± 30 and 546 ± 27 µm, respectively, p=0.005) were significantly thinner in PXS patients. Visual acuity was significantly lower (0.52 ± 0.37 versus 0.88 ± 0.23, p<0.001) and axial length was significantly longer (23.9 ± 0.70 mm versus 23.2 ± 0.90 mm, p=0.001) in the PXS eyes than in the control eyes. There were no statistically significant differences in the mean values of keratometry, anterior chamber angle, anterior chamber depth, corneal volume, and anterior chamber volume between the PXS and control eyes. Conclusions: The patients with PXS had thinner corneas, worse visual acuity, and longer axial length compared with those in the healthy controls.

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“…12 Birçok çalışmada, DM ile MKK arasında bir ilişki olduğu belirtilmiştir. [13][14][15] Özcura ve ark., Tip 2 DM'li hastaların MKK'lerinin kontrol grubuna göre daha yüksek olduğunu bildirdikleri çalışmalarında, MKK'deki artışın DM'nin süresiyle ve DR varlığı ile ilişki göstermediğini belirtmişlerdir.…”

Section: Gereç Ve Yöntemlerunclassified

“…[13][14][15]19 Çalışmamızda, diyabetli gözlerde MKK'nin kontrol grubuna göre yüksek olduğunu saptadık. Lee ve ark., DM'li grupta MKK'nın endotel fonksiyon bozukluğu sonucu oluşan hidrasyona bağlı olarak daha kalın olduğunu bildirmişlerdir.…”

Section: İstati̇sti̇ksel Anali̇zunclassified

Evaluation of Central Corneal Thickness Using Spectral-Domain Optical Coherence Tomography in Patients with Diabetes Mellitus

Bayhan¹,

Bayhan²,

Muhafız³

et al. 2015

Turkiye Klinikleri J Ophthalmol

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A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Diabetes mellitus; kornea; tomografi, optik koherens A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To compare the central corneal thickness (CCT) in patients with diabetes mellitus (DM) and healthy control subjects and to evaluate the association between diabetic parameters and CCT. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : In this prospective study, 48 eyes of 48 diabetic patients and 48 eyes of 48 control subjects were evaluated. Diabetic patients and control group were compared in terms of CCT measured by spectral domain optical coherence tomography (RTVue, Optovue). The effects of age, sex, blood glucose concentration, percentage of hemoglobin A1c (HbA1c), insulin usage, presence of diabetic retinopathy, and duration of DM on CCT were assessed. R Re es su ul lt ts s: :The CCT was significantly greater in diabetic group (545.13±34.01 µm) compared with control group (530.73±22.82 µm) (p=0.004). CCT was moderately correlated with HbA1c (r=0.558, p<0.01) and weakly correlated with blood glucose (r=0.359, p=0.047). Multiple regression analysis evaluating the effects of age, sex, blood glucose concentration, HbA1c, insulin usage, presence of diabetic retinopathy, and duration of DM on CCT showed that HbA1c value was the only significant factor associated with increased CCT. C Co on nc cl lu us si io on n: : The CCT of diabetic patients is greater than normal individuals and only factor associated with this increment is HbA1c value. Diagnosis and management of glaucoma in diabetic patients should be evaluated carefully.K Ke ey y W Wo or rd ds s: : Diabetes mellitus; cornea; tomography, optical coherence T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J O Op ph ht th ha al lm mo ol l 2 20 01 15 5; ;2 24 4( (3 3) ): :1 15 52 2--6 6

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Central Corneal Thickness and Corneal Curvature in Pseudoexfoliation Syndrome With and Without Glaucoma

Cited by 38 publications

References 30 publications

Chronomorphological and pressure changes in a sign of aging - pseudoexfoliation of the eye

Chronomorphological and pressure changes in a sign of aging - pseudoexfoliation of the eye

Evaluation of anterior segment parameters in patients with pseudoexfoliation syndrome using Scheimpflug imaging

Evaluation of Central Corneal Thickness Using Spectral-Domain Optical Coherence Tomography in Patients with Diabetes Mellitus

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