Central Nervous System Infections

Khalbuss, Walid E.; Michelow, Pam; Pantanowitz, Liron

doi:10.1007/978-1-4614-0242-8_9

Cited by 3 publications

(5 citation statements)

References 9 publications

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“…58 Because aspirates often produce hypocellular specimens that generally exhibit extensive extracellular stringy mucus, few macrophages, and bland epithelial cells, they are a major source of false-negative salivary gland diagnoses. 52,59 Histiocytes and mucinous cells can seem similar. Histiocytoid cells can be round or columnar, have a large cytoplasm that is finely vacuolated, and often have tiny, homogenous nuclei that are positioned eccentrically.…”

Section: Mucinous C Ys Ti C Le S I On Smentioning

confidence: 99%

“…The FNA of these lesions typically reveals hypocellular mucinous material content, sometimes accompanied by inflammatory cells and, in the case of retention cysts, also a dearth of degenerating cuboidal, oncocytic, or squamoid epithelial cells 52 . Furthermore, findings of a high amylase content, histiocytes, and no epithelial cells are helpful in differentiating ranulas from other oral or neck masses such as thyroglossal duct cyst, branchial cleft cyst, cystic hygroma/lymphatic malformation, intramuscular hemangioma, lymphangioma, abscess, or dermoid 49 …”

Section: Non‐neoplastic Mucinous Cystsmentioning

confidence: 99%

“…Epidermoid cells resemble bland, homogeneous flat sheets with well‐defined cellular boundaries and squamoid, thick cytoplasm 58 . Because aspirates often produce hypocellular specimens that generally exhibit extensive extracellular stringy mucus, few macrophages, and bland epithelial cells, they are a major source of false‐negative salivary gland diagnoses 52,59 . Histiocytes and mucinous cells can seem similar.…”

Section: Mucinous Cystic Lesionsmentioning

confidence: 99%

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Cystic lesions in the salivary gland. Pitfalls to be avoided on cytology

et al. 2023

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Cystic lesions of the salivary glands are very uncommon entities. However, on occasion, some neoplasms of the salivary glands show a cystic component, which may be predominant or only partially cystic. Basal cell adenoma, canalicular adenoma, oncocytoma, sebaceous adenoma, intraductal papilloma, epithelial‐myoepithelial carcinoma, intraductal carcinoma, and secretory carcinoma are such cystic entities. Cystic degeneration and necrosis, which can develop within solid tumours, represent another possibility. The ability to recognise this type of lesion is a challenge in diagnostic cytology because hypocellular fluid is frequently recovered. Furthermore, evaluating all of the differential diagnoses for cystic lesions of the salivary glands is helpful in obtaining the correct diagnosis. Herein, we evaluate the various types of cystic lesions within the salivary glands.

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Section: Mucinous C Ys Ti C Le S I On Smentioning

confidence: 99%

Section: Non‐neoplastic Mucinous Cystsmentioning

confidence: 99%

Section: Mucinous Cystic Lesionsmentioning

confidence: 99%

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Cystic lesions in the salivary gland. Pitfalls to be avoided on cytology

et al. 2023

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“…In chronic infections there is more of a predominant mononuclear leukocytosis. 65 Culture, immunofluorescence, or molecular testing may also be required for confirmation.…”

Section: P a R Asi T Ic I Nf E Cti On Smentioning

confidence: 99%

Cerebrospinal fluid cytology in nonmalignant aseptic meningeal disorders

Martínez‐Girón¹,

Pantanowitz

2017

Diagnostic Cytopathology

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Cerebrospinal fluid cytology examination is a common and reliable primary and/or complementary procedure for the diagnosis of central nervous system (CNS) disorders. This review provides an update of aseptic meningeal disorders that may be encountered in cytopathology practice. The article covers the cytological findings and helpful ancillary studies needed of nonmalignant aseptic CNS disorders such as viral, bacterial, fungal and parasitic infections, and other noninfectious diseases, such as Mollaret's meningitis (recurrent benign lymphocytic meningitis), Guillain-Barré syndrome, multiple Sclerosis, subarachnoid haemorrhage, and drug-induced disorders.

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“…Tachyzoites, which predominate in acute cases, are small, 4‐8 × 2‐3 μm, oval, crescent or banana‐shaped structures, which are difficult to identify, especially when there is necrosis . Tachyzoites have a pointed anterior and a rounded posterior end, towards which a round nucleus may be visible . Their small size, inconsistent staining with hematoxylin and eosin (H&E), and admixture with necrotic debris makes them easy to overlook, disregard or misinterpret as stain artifacts, non‐specific calcifications, or nuclear debris.…”

mentioning

confidence: 99%