Central Neurological Complications of Hypoparathyroidism

The Search for Causes of Idiopathic Intracranial Hypertension

“…Idiopathic intracranial hypertension has developed following withdrawal of corticosteroid therapy, most often re¬ ported in children.29'31 Idiopathic in¬ tracranial hypertension has also been reported in patients with chronic ad¬ renal insufficiency.32·33 Additionally, but less commonly, IIH has been ob¬ served in patients being treated with a corticosteroid (triamcinolone) without tapering or withdrawal.34·35 Other en¬ docrine disorders have occurred con¬ currently with IIH, including hypothy¬ roidism,3638 hyperthyroidism,39 and hypoparathyroidism. 40 Idiopathic intracranial hyperten¬ sion has been reported in patients with a multitude of preexisting or concur¬ rent disease states. Iron deficiency anemia,13·41 blood loss anemia,42 perni¬ cious anemia,43 and aplastic anemia44 have all been reported in persons with UH.…”

Calcium Metabolism

“…Other hypocalccemic manifestations arise in or result from involvement of the central nervous system. Mental symptoms of some degree are pr~bably universal, epilepsy and electroencephalographic abnormalities are not uncommon, while raised intracranial tension with papillcedema and also calcification of the basal ganglia are seen, particulady in hypoparathyroidism (Sugar, 1953;Grant, 1953).…”