Central retinal venous occlusion in an otherwise-healthy child

Central Retinal Vein Occlusion in 12-Year-Old Girl With Methylenetetrahydrofolate Reductase Mutation: A Case Report and Review of the Literature

“…Among these, neovascularization occurred in six cases, 4–9 four being diagnosed at presentation. 5–8 The longest time interval previously reported between the initial CRVO and neovascularization was 8 months in a case of a CRVO secondary to antiphospholipid syndrome. 9…”

“…To our knowledge, there are at least 24 case reports of pediatric CRVO in the literature to date with patients ranging from 20 months to 18 years. Among these, neovascularization occurred in six cases, [4][5][6][7][8][9] four being diagnosed at presentation. [5][6][7][8] The longest time interval previously reported between the initial CRVO and neovascularization was 8 months in a case of a CRVO secondary to antiphospholipid syndrome.…”

“…Among these, neovascularization occurred in six cases, [4][5][6][7][8][9] four being diagnosed at presentation. [5][6][7][8] The longest time interval previously reported between the initial CRVO and neovascularization was 8 months in a case of a CRVO secondary to antiphospholipid syndrome. 9 Our report is unique in that the patient developed neovascularization 12 years after the initial insult.…”

Unilateral central retinal vein occlusion as a first manifestation of diabetes mellitus in a ten-year-old girl

“…To the best of our knowledge, this is the first description of CRVO as a first presentation of diabetes mellitus in pediatric age group. Among the few previous case reports of children with retinal venous occlusion are; a 14 years old girl who was positive for Bartonella henselae (Ischemic central retinal vein occlusion), 5 an otherwise healthy 6 years old girl (Central retinal venous occlusion), 6 two cases of otherwise healthy 13 years old boys (Central retinal vein occlusion),7, 8 a 15 years old girl with SLE and anti-phospholipid antibodies (Central retinal vein occlusion), 9 a 12 months old girl with exanthema subitum associated with human herpes virus 6 (central retinal vein occlusion), 10 a 20 months old boy with cyanotic heart disease (central retinal vein occlusion), 11 a 13 years old girl with sarcoidosis (branch retinal vein occlusion), 12 a 14 years old girl with infective endocarditis (combined central retinal vein occlusion and central retinal artery occlusion) 13 …”