Central skull base lymphoma in children: MR and CT features

Choi, Hei Kyung; Cheon, Jung Eun; Kim, In One; Youn, Byung Jae; Jung, Ah Young; Shin, Sei One; Kim, Woo Sun; Yeon, Kyung Mo

doi:10.1007/s00247-008-0912-z

Cited by 22 publications

(9 citation statements)

References 13 publications

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“…The described etiologies for CS tumors have included infectious disease, Tolosa-Hunt syndrome (THS), aneurysm, thrombosis, and neoplasms [12]. Although neoplasms originating from the CS are rare in children, several case reports concerning malignant lymphoma in the CS have been published [13, 14]. In the present case, MRA ruled out vascular lesions.…”

Section: Discussionmentioning

confidence: 76%

Atypical teratoid rhabdoid tumor in the cavernous sinus of a toddler presenting with oculomotor nerve palsy

et al. 2014

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IntroductionAtypical teratoid rhabdoid tumor (ATRT) is a rare, highly malignant, and aggressive tumor of infancy. Although the prognosis of ATRT has been extremely poor, recently, the first prospective study for ATRT demonstrated improvement of prognosis. On the other hands, oculomotor nerve palsy is rare in children and the most frequent etiology is congenital. To our knowledge, only a few ATRT cases presenting with oculomotor nerve palsy have been reported, but ATRT originating from the cavernous sinus (CS) has not yet been reported.Case reportAn 18-month-old girl with right oculomotor nerve palsy was admitted, and a small mass in the right CS was detected with brain MRI. Although she received steroid pulse therapy and antimicrobial therapy, the mass continued to enlarge. One month after admission, the mass was partially resected and diagnosed as ATRT. Multimodal therapy including anthracycline-based chemotherapy, intrathecal therapy, and cranial irradiation was performed. Twenty-nine months after resection, she was alive without tumor relapse, but the oculomotor nerve palsy persisted.ConclusionThis is the first reported case of ATRT located in the CS presenting with oculomotor nerve palsy. This case was successfully treated with partial removal of the tumor, a new chemotherapy regimen for ATRT and cranial X-ray irradiation.

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Section: Discussionmentioning

confidence: 76%

Atypical teratoid rhabdoid tumor in the cavernous sinus of a toddler presenting with oculomotor nerve palsy

et al. 2014

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“…CT images of sinonasal lymphoma show high attenuation with permeative bone destruction without calcification, chondroid or osteoid matrix formation, haemorrhage and necrosis 11 12. On the other hand, there have been few reports about imaging features of sphenoid lymphomas.…”

Section: Discussionmentioning

confidence: 99%

Diffuse large B-cell lymphoma in the sphenoid sinus mimicking fibrous dysplasia in CT and MRI

Yoshihara

Kondo²,

Ochi

2014

BMJ Case Reports

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SUMMARYWe present a 70-year-old man with lymphoma who presented with a right eye movement disorder. CT examinations showed 'ground-glass' appearance extending around the right sphenoid sinus which suggested fibrous dysplasia. However, biopsy from the mass histologically proved it to be diffusing large B-cell lymphoma and positron emission tomography examinations revealed increased fluorodeoxyglucose (FDG) uptake around the right sphenoid bone and multiple spinal bones. After chemotherapy for lymphoma, abnormal FDG uptake disappeared from the body. BACKGROUND

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“…44 Imaging is useful in these cases to help differentiate lymphoma from sarcoma or carcinoma with findings of homogeneous tumor that are isointense to brain on T2 MRI images and highly attenuating with smooth borders on CT being typical. 45 For most cases of lymphoma that involve the temporal bone, there is also disease involvement at another site within the head and neck-often a site more easily approached for a biopsy. As with most lymphomas in the head and neck, surgery is limited to tissue biopsy to establish a diagnosis and to prompt primary chemotherapy and/or radiation therapy.…”

Section: Lymphoma and Carcinomamentioning

confidence: 99%

Rhabdomyosarcoma and Other Pediatric Temporal Bone Malignancies

Gluth

2015

Otolaryngologic Clinics of North America

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Central skull base lymphoma in children: MR and CT features

Abstract: Lymphoma involving the central skull base in children is visualized as an isointense mass on T2-weighted MRI with marked contrast enhancement and adjacent dural thickening, and as a highly attenuating mass on noncontrast CT with permeative or erosive bone destruction patterns.

Cited by 22 publications

References 13 publications

Atypical teratoid rhabdoid tumor in the cavernous sinus of a toddler presenting with oculomotor nerve palsy

Atypical teratoid rhabdoid tumor in the cavernous sinus of a toddler presenting with oculomotor nerve palsy

Diffuse large B-cell lymphoma in the sphenoid sinus mimicking fibrous dysplasia in CT and MRI

Rhabdomyosarcoma and Other Pediatric Temporal Bone Malignancies

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