Cephacetrile, a New Cephalosporin, in the Treatment of Urinary Tract Infections

Abstract

Cephacetrile (the sodium salt of 7-cyanoacetamido cephalosporanic acid) was used to treat 21 cases of urinary tract infections in patients from a general urological ward. The patients were followed up at 6 weeks after completing the course of antibiotic and 75% had a bacteriological cure. Serum and urinary levels of cephacetrile were measured and toxicological data were collected on all patients. No adverse effects attributable to the drug were noted.