Cerebellar afferents from the lateral reticular nucleus in the rat

Connections of the Lateral Reticular Nucleus to the Lateral Vestibular Nucleus in the Rat. An Anterograde Tracing Study with Phaseolus vulgaris Leucoagglutinin

“…Spinal afferents to the LRt have been described in various animals including the cat (Brodal, 1949;Morin et al, 1966;Kunzle, 1973;Corvaja et al, 1977) Ruigrok and Cella, 1995). Mossy fibre projections arising from the LRt terminate in large areas of the cerebellar cortex and in addition terminal arborizations have been found within the cerebellar nuclei, especially in the interposed and fastigial nuclei (cat: Kiinzle, 1975;Dietrichs and Walberg, 1979;Dietrichs, 1983; rat: Hrycyshyn et al, 1982; Ghazi et al, 1987;Payne, 1987). Most of these studies have been performed with the aid of retrograde tracing studies or with relatively large LRt injections with anterograde tracers such as tritiated leucine or wheatgerm agglutinin coupled to horseradish peroxidase.…”

Distribution of neurons in the lateral reticular nucleus projecting to cervical, thoracic, and lumbar segments of the spinal cord in the rat

“…It has long been known that the lateral reticular nucleus, located at the medullary reticular formation, is one of the major precerebelkr nulcei that relay information to the cerebellum (Payne, 1987). It receives massive sensory-or motor-related inputs from the spinal cord as well as the red nucleus and the cerebral cortex (Shokunbi et al, 1986;Wiesendanger and Wiesendanger, 1987).…”

“…It was reported in the rat that neurons in the subtrigeminal region of the LRN send efferent fibers to various lobules of the vermis and cerebelkr hemispheres, whereas those in the parvocellular division specifically do to the pyramis and copula pyramidis of the cerebellum (Eisenman, 1982;Payne, 1987).…”

“…The lateral reticular nucleus (LRN) is one of the precerebellar nuclei that provide significant mossy fiber projections to the cerebellum of the rat (Payne, 1987). The LRN receives massive sensory input from the spinal cord via two monosynaptic pathways, the bilateral ventral flexor reflex tract and the ipsikteral forelimb tract (Ekerot, 1990a;1990b).…”

Topographical organisation within the lateral reticular nucleus mossy fibre projection to the c1 and c2 zones in the rostral paramedian lobule of the cat cerebellum

“…The posterior lobe paramedian lobule (PML), for example, has been shown to have a mossy fibre projection that arises almost exclusively from the ipsilateral LRN, whereas the anterior lobe projection is bilateral, with a heavy ipsilateral preponderance (cat : Brodal, 1975;Dietrichs and Walberg, 1979;rat: Hrycyshyn et al, 1982;Ghazi et al, 1987;Payne, 1987). A somatotopical organisation has also been demonstrated in cat, whereby medial parts of the LRN (that correspond mostly to the magnocellular region) project to the ''forelimb-receiving areas'' of the paravermal cortex, i.e., the caudal anterior lobe and the rostral PML, whereas lateral parts of the LRN (that correspond mostly to the parvicellular region) project to ''hindlimb-receiving areas,'' i.e., the rostral anterior lobe and the caudal PML (Brodal, 1975; see also Dietrichs and Walberg, 1979).…”