Cerebral abscess and calvarial osteomyelitis due to Burkholderia pseudomallei

Bommakanti, Kalyan; Ankathi, Praveen; Uma, Prasad; Malladi, Subbalaxmi V. S.; Laxmi, Vijay

doi:10.4103/0028-3886.72188

Cited by 11 publications

(9 citation statements)

References 6 publications

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“…Osteomyelitis of the skull bones can be a primary focus with a contiguous spread to the underlying parenchyma [4] as noted in our study [14]. We documented an unusual case of B. pseudomallei calvarial osteomyelitis that had spread to both the parietal lobes and medially extended up to the sagittal sinus [14].…”

Section: Discussionsupporting

confidence: 51%

“…We documented an unusual case of B. pseudomallei calvarial osteomyelitis that had spread to both the parietal lobes and medially extended up to the sagittal sinus [14]. There were two other cases of calvarial osteomyelitis with sterile abscesses in the study group II.…”

Section: Discussionmentioning

confidence: 99%

“…B. pseudomallei (2 cases): One patient with melioidosis had presented with fever and abdominal pain and developed calvarial osteomyelitis and multiple parietal and sagittal sinus abscesses [14]. Another patient with a splenic abscess due to B. pseudomallei developed a frontal lobe brain abscess.…”

Section: Microbial Spectrummentioning

confidence: 99%

“…The microbiologist should be well versed with the colony morphology and the antibiogram of these important yet not very fastidious organisms. Ceftazidime remains the drug of choice in the early phase of treatment, followed by a prolonged therapy with cotrimoxazole [14]. …”

Section: Culture For Various Organismsmentioning

confidence: 99%

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Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Lakshmi

Umabala

Anuradha

et al. 2011

Pathology Research International

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Intracranial abscesses are life-threatening infections that pose a diagnostic challenge not only to the neurosurgeon but also to the microbiologists. Detailed studies documenting the spectrum of infecting agents involved in brain abscesses are limited from India. Materials and Methods. This is a retrospective analysis of 352 samples from 1987 to 2010 analyzed at a tertiary care hospital in South India from 1987 to 2010, to document the changing trends with time. Results. The age of the patients ranged from 2 to 80 years, a larger number of males being affected. Otogenic infections were the most common cause while cryptogenic abscesses were 20%. Gram stain and culture positivity were 78% each. Gram-positive and negative facultative aerobes and obligate anaerobes were also on the rise. Unusual organisms, like Burkholderia pseudomallei, Salmonella typhi, Nocardia species, Cladosporium bantiana, Fonsecaea pedrosoi, Entamoeba histolytica, and Acanthamoeba were also isolated and/or detected from the brain abscesses aspirate or resected tissue. Summary. New and emerging pathogens associated with brain abscess, especially in immunosuppressed individuals, have renewed the necessity of an early detection, and it will be of great value in appropriate management of patients with brain abscess.

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Section: Discussionsupporting

confidence: 51%

Section: Discussionmentioning

confidence: 99%

Section: Microbial Spectrummentioning

confidence: 99%

Section: Culture For Various Organismsmentioning

confidence: 99%

See 2 more Smart Citations

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Lakshmi

Umabala

Anuradha

et al. 2011

Pathology Research International

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“…Current understanding of the imaging features of CNS melioidosis is derived from isolated case reports or small case series in the microbiology literature . Variable imaging manifestations have been reported and include cerebral abscesses, meningitis, extraaxial collections, and skull osteomyelitis.…”

Section: Introductionmentioning

confidence: 99%

Neuromelioidosis: Craniospinal MRI Findings in Burkholderia pseudomallei Infection

Hsu

Singh

Kwan

et al. 2015

Journal of Neuroimaging

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Spread of microabscesses along white matter tracts and frequent trigeminal nerve involvement are unique imaging characteristics of CNS melioidosis. These findings may provide insight into potential mechanisms for B. pseuodomallei entry into the CNS through direct axonal transport in cranial nerves bypassing the blood brain barrier. Prompt recognition of the neuroimaging features of this potentially fatal infection may allow for early microbiological culture and treatment.

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Cavernous malformation of the optic pathway mimicking optic glioma: a case report

et al. 2014

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Purpose Optic pathway cavernous malformations (CMs) are extremely rare, accounting for less than 1 % of all intracranial CMs. We report a case of optic pathway CM mimicking optic glioma because the initial magnetic resonance (MR) images did not disclose hemorrhagic findings such as popcorn-like lesion or hemosiderin ring. Methods A 20-year-old woman presented with subacute left visual acuity loss and visual field defect and was referred to our hospital. Initial MR imaging findings were suggestive of optic glioma. Second MR imaging demonstrated hemorrhagic findings, but the hemorrhage was considered to be intratumoral hemorrhage from left optic pilocytic astrocytoma. She underwent radiochemotherapy and intravenous administration of corticosteroids but her symptoms deteriorated. Third and fourth MR imaging revealed enlargement of the hematoma. Therefore, the radiation therapy was interrupted at a delivered dose of 16.2 Gy, and craniotomy was performed to preserve residual right visual field. The lesion was totally removed and the histological diagnosis was CM. Her right visual field was preserved, but not improved. Results The present case and previous cases suggest that optic pathway CMs sometimes do not initially manifest with signs of hemorrhage, so CMs should be included in the differential diagnosis of optic pathway lesions.Conclusions Histological confirmation with preparation for total resection should be considered for rapidly progressive cases even if the neuroimaging findings are compatible with optic glioma.

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Cerebral abscess and calvarial osteomyelitis due to Burkholderia pseudomallei

Cited by 11 publications

References 6 publications

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Neuromelioidosis: Craniospinal MRI Findings in Burkholderia pseudomallei Infection

Cavernous malformation of the optic pathway mimicking optic glioma: a case report

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