Cerebral angiographic and clinical differences in carotid system transient ischemic attacks between American Caucasian and Japanese patients.

Abstract

Cerebral angiographic findings of 32 Japanese patients with carotid system TIA's were compared with those of an equal number of age and sex matched American Caucasians. The end points included irregularity, ulceration, stenosis or occlusion of the carotid artery appropriate to the side of TIA. Atherosclerotic changes were found in 27 patients (84.4%) of the Japanese and 30 patients (93.7%) of the American patients. Mild lesions (49% stenosis and below) were similar in either frequency of topography between both groups; namely 25 intracranial and 17 extracranial lesions in Japanese as well as 29 intracranial and 10 extracranial in Caucasian patients. There was, however, an extra-intracranial difference in severe lesions (50% stenosis and above) between American Caucasian and Japanese patients; 10 of 12 severe lesions in Japanese were located intracranially, while 17 of 20 severe lesions present in the American group occurred in the extracranial portion of the internal or common carotid arteries.

Transient cerebral ischemic attacks in a Japanese community, Hisayama, Japan.

“…Twelve cases were detected through these procedures as possible TIA patients. Thus, the prevalence of TIAs among the Hisayama residents was 4.9/1,000, lower than the prevalence of TIA (13.8/1,000) in the white population of Evans County, Georgia, 13 and that (63/1,000) in an elderly, poor population of Chicago. 16 The mechanism of TIAs for Japanese may be different from that for whites.…”

Relation between blood lipids, lipoproteins, and cerebrovascular atherosclerosis. A review.

“…Only two included blacks, and in these, results were not presented separately for each race. Because blacks 10 -48 ' 49 as well as Japanese 50 tend to have more intracranial atherosclerosis than American Caucasians, it is important to study and report separately the relation between plasma lipid concentrations and cerebrovascular atherosclerosis for different racial groups. This is especially important if, as Heyden et al 49 suggested, there are etiologic and pathogenetic ethnic differences between vascular diseases of the extracranial and intracranial cerebral arteries.…”

Frequency and Outcome of Carotid Atheromatous Disease in Patients With Stroke in Pakistan

“…10 Racial differences in the distribution of extracranial and cerebral vascular occlusive disease are well-documented. [11][12][13][14][15][16][17][18] Bauer et al 19 first suggested racial differences in the distribution of cerebral atherosclerosis in an angiographic study of patients admitted to a single hospital. The amount of carotid atherosclerosis seen among South Asians is much lower even after adjustment for age, sex, and recruiting center.…”