Cerebral Embolic Infarction Caused by Aortic Arch Thrombus with Iron Deficiency Anemia

Abstract

Atherosclerotic lesions at the aortic arch are recognized as critical sources of embolic strokes. However, there have been few case reports of aortic arch thrombus occurring without atherosclerotic changes, especially those related to iron deficiency anemia (IDA). A 44-year-old woman was admitted due to rapid-onset right hemiparesis and aphasia. Etiological investigations for cerebral infarction revealed no abnormality other than IDA. This is a rare case of cerebral embolic infarction caused by an aortic arch thrombus with IDA in a middle-aged woman.

Application of fucoidan as treatment for cardiovascular and cerebrovascular diseases

“… 87 Late atherosclerotic plaques invade the arterial lumen, hinder blood flow, and lead to tissue ischemia, causing thrombosis. 88 In addition, the lipid necrotic core and the thin fibrous cap of high-risk plaques lead to plaque instability and rupture due to inflammatory cell and diffuse calcification infiltration. The interaction between exposed atherosclerotic plaque components, platelet receptors, and coagulation factors eventually leads to platelet activation and aggregation, followed by thrombosis, which damages the arterial lumen.…”