Cerebral ganglioglioma and neurofibromatosis type I

Parizel, Paul M.; Martin, J. J.; Vyve, M. Van; Hauwe, Luc van den; Schepper, A. M. De

doi:10.1007/bf00587825

Cited by 15 publications

(8 citation statements)

References 11 publications

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“…The cysts are hypointense on T1-weighted MRI and FLAIR, and hyperintense on T2-weighted MRI. Alternatively, gangliogliomas have been histologically with this tumor, although one patient was reported to have both neurofibromatosis type 1 (NF-1) and a ganglioglioma (Parizel et al 1991). The solid component displays variable enhancement patterns after gadolinium administration, but can be homogeneous or patchy (Zhang et al 2008).…”

Section: Ganglioglioma Demographicsmentioning

confidence: 99%

Uncommon glial tumors

Chen¹,

Elder²,

González-Gómez³

et al. 2012

Brain Tumors

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Section: Ganglioglioma Demographicsmentioning

confidence: 99%

Uncommon glial tumors

Chen¹,

Elder²,

González-Gómez³

et al. 2012

Brain Tumors

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“…12 Glioneuronal tumours have rarely been associated with NF1, and our cases further highlight the variety of tumours that occur in this condition. Parizel et al 4 described a case of frontal ganglioglioma in a patient with NF1 and seizures. Two other patients who presented with seizures have been reported with DNT and NF1.…”

Section: Discussionmentioning

confidence: 98%

“…2;3 Partially or completely differentiated glioneuronal tumours such as gangliogliomas and dysembryoplastic neuroepithelial tumours (DNTs) have rarely been reported in NF1. [4][5][6][7] We describe the radiological and pathological features of these low-grade lesions in two patients with NF1.…”

Section: Introductionmentioning

confidence: 99%

Glioneuronal tumours in neurofibromatosis type 1: MRI-pathological study

Fedi

Mitchell²,

Gutmann³

et al. 2004

Journal of Clinical Neuroscience

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“…The occurrence of gangliogliomas in NF1 is established [6], but has not yet been reported in the cerebellum. The general assumption is that these tumors have no specific characteristics and are histologically identical to sporadic tumors [14].…”

Section: Discussionmentioning

confidence: 99%

Cerebellar gliomas in children with NF1: pathology and surgery

Vinchon¹,

Soto-Ares

et al. 2000

Child's Nerv Syst

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Cerebellar gliomas associated with NF1 (CGNF1) are rarely reported in the literature, and they are considered to be malignant in a high proportion of cases. In an attempt to improve the definition of this disease and clarify its management, we reviewed our patients with CGNF1 and compared their tumors with sporadic cerebellar gliomas (SGC). We operated on six children with CGNF1, all but one of whom were asymptomatic. They represented one-tenth of all pediatric cerebellar gliomas, and one third of NF1-associated gliomas seen in our institution. CGNF1 appeared at a later age than SCG. They are seated near the roof of the IV ventricle and are not related to white matter hypersignal hamartomas. Most of these tumors showed radiological progression. They were four pilocytic astrocytomas, one ganglioglioma, and one malignant astrocytoma. One patient had tumor recurrence after 8 years, and the others are still disease free. The overall outcome appeared to be better for GCNF1 than for SCG. On account of the regular growth, uncertain pathology, and good surgical outcome, we advocate systematic resection of these tumors.

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Cerebral ganglioglioma and neurofibromatosis type I

Cited by 15 publications

References 11 publications

Uncommon glial tumors

Uncommon glial tumors

Glioneuronal tumours in neurofibromatosis type 1: MRI-pathological study

Cerebellar gliomas in children with NF1: pathology and surgery

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