Cervical Cancer Incidence in Young U.S. Females After Human Papillomavirus Vaccine Introduction

Guo, Fangjian; Cofie, Leslie E.; Berenson, Abbey B.

doi:10.1016/j.amepre.2018.03.013

Cited by 125 publications

(92 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cervical and endometrial cancer are the most common gynecologic cancer worldwide . Because of the anatomic advantage of being able to place catheters directly within the tumor, a high dose can be given locally while still limiting the dose to neighboring organs.…”

Section: Introductionmentioning

confidence: 99%

Clinical implementation, logistics and workflow guide for MRI image based interstitial HDR brachytherapy for gynecological cancers

Zhang

Donnelly

Strauss

et al. 2019

J Applied Clin Med Phys

View full text Add to dashboard Cite

Interstitial brachytherapy (IBT) is often utilized to treat women with bulky endometrial or cervical cancers not amendable to intracavitary treatments. A modern trend in IBT is the utilization of magnetic resonance imaging (MRI) with a high dose rate (HDR) afterloader for conformal 3D image‐based treatments. The challenging part of this procedure is to properly complete many sequenced and co‐related physics preparations. We presented the physics preparations and clinical workflow required for implementing MRI‐based HDR IBT (MRI‐HDR‐IBT) of gynecologic cancer patients in a high‐volume brachytherapy center. The present document is designed to focus on the clinical steps required from a physicist’s standpoint. Those steps include: (a) testing IBT equipment with MRI scanner, (b) preparation of templates and catheters, (c) preparation of MRI line markers, (d) acquisition, importation and registration of MRI images, (e) development of treatment plans and (f) treatment evaluation and documentation. The checklists of imaging acquisition, registration and plan development are also presented. Based on the TG‐100 recommendations, a workflow chart, a fault tree analysis and an error‐solution table listing the speculated errors and solutions of each step are provided. Our workflow and practice indicated the MRI‐HDR‐IBT is achievable in most radiation oncology clinics if the following equipment is available: MRI scanner, CT (computed tomography) scanner, MRI/CT compatible templates and applicators, MRI line markers, HDR afterloader and a brachytherapy treatment planning system capable of utilizing MRI images. The OR/procedure room availability and anesthesiology support are also important. The techniques and approaches adopted from the GEC‐ESTRO (Groupe Européen de Curiethérapie ‐ European Society for Therapeutic Radiology and Oncology) recommendations and other publications are proven to be feasible. The MRI‐HDR‐IBT program can be developed over time and progressively validated through clinical experience, this document is expected to serve as a reference workflow guideline for implementing and performing the procedure.

show abstract

Section: Introductionmentioning

confidence: 99%

Clinical implementation, logistics and workflow guide for MRI image based interstitial HDR brachytherapy for gynecological cancers

Zhang

Donnelly

Strauss

et al. 2019

J Applied Clin Med Phys

View full text Add to dashboard Cite

show abstract

“…This strategy has shown promise against multiple viral-based cancers. Indeed, vaccination against oncogenic viruses including hepatitis B and human papillomavirus have led to reductions in hepatic [139] and cervical [140] cancers, respectively. However, for non-virally associated cancers, a target antigen and clinical setting to administer preventive vaccines is often less clear.…”

Section: Preventive Cancer Vaccinesmentioning

confidence: 99%

Talkin’ Toxins: From Coley’s to Modern Cancer Immunotherapy

Carlson

Flíckinger

Snook

2020

Toxins

View full text Add to dashboard Cite

The ability of the immune system to precisely target and eliminate aberrant or infected cells has long been studied in the field of infectious diseases. Attempts to define and exploit these potent immunological processes in the fight against cancer has been a longstanding effort dating back over 100 years to when Dr. William Coley purposefully infected cancer patients with a cocktail of heat-killed bacteria to stimulate anti-cancer immune processes. Although the field of cancer immunotherapy has been dotted with skepticism at times, the success of immune checkpoint inhibitors and recent FDA approvals of autologous cell therapies have pivoted immunotherapy to center stage as one of the most promising strategies to treat cancer. This review aims to summarize historic milestones throughout the field of cancer immunotherapy as well as highlight current and promising immunotherapies in development.

show abstract

“…HPV immunization can prevent up to 70% of cases of cervical cancer due to HPV as well as 90% of genital warts. 4 The US Food and Drug Administration (FDA) has approved 3 HPV vaccines: • Gardasil 9 targets HPV types 6,11,16…”

Section: ■ Types Of Hpv Vaccinesmentioning

confidence: 99%

Human papillomavirus in 2019: An update on cervical cancer prevention and screening guidelines

Zhang

Batur²

2019

CCJM

View full text Add to dashboard Cite

The human papillomavirus (HPV) causes most cases of cervical cancer. Healthcare providers can help prevent this cancer by recommending HPV vaccination when appropriate, regularly screening women for cervical cancer, and following up on abnormal test results. KEY POINTSImmunization against HPV can prevent up to 70% of HPV-related cervical cancer cases.Gardasil 9 is the only HPV vaccine currently available in the United States and is now approved for use in males and females between the ages of 9 and 45.

show abstract

Cervical Cancer Incidence in Young U.S. Females After Human Papillomavirus Vaccine Introduction

Abstract: A significant decrease in the incidence of cervical cancer among young females after the introduction of human papillomavirus vaccine may indicate early effects of human papillomavirus vaccination.

Cited by 125 publications

References 33 publications

Clinical implementation, logistics and workflow guide for MRI image based interstitial HDR brachytherapy for gynecological cancers

Clinical implementation, logistics and workflow guide for MRI image based interstitial HDR brachytherapy for gynecological cancers

Talkin’ Toxins: From Coley’s to Modern Cancer Immunotherapy

Human papillomavirus in 2019: An update on cervical cancer prevention and screening guidelines

Contact Info

Product

Resources

About