Cervical Castleman disease: CT study with angiographic correlation.

Abstract

The computed tomographic (CT) appearance, angiographic appearance, and clinical features of a patient with cervical Castleman disease, an uncommon disease of benign lymph node hyperplasia, are reported. CT scans showed a densely enhancing cervical mass. On external carotid angiography, the mass was seen as hypervascular with a capillary blush. Differential diagnosis included carotid body chemodectoma, vagal neuroma, tumor of the salivary gland, tuberculous adenitis and other granulomatous diseases, inflammatory lymph nodes, metastatic disease, and lymphoma.

Isolated Involvement of Cervical Lymph Nodes in Castleman’s Disease in a Young Patient: A Rare Presentation

“…These are the typical features of Castleman's disease on CT scan. (7,8) This brilliant enhancement suggests high vascularity and it is seen in hyaline-vascular variant due to its greater vascularity. On imaging three patterns of involvement have been described, which includes a solitary non-invasive mass; it is most commonly seen in 50% of cases, a dominant infiltrative mass with associated lymphadenopathy seen in 40% of cases and a matted lymphadenopathy without a dominant mass seen in 10% of cases.…”

Castleman's Disease of the Tracheal: A Case Report

“…The main imaging features of focal CD reviewed that was [8]: isolated, large and homogeneous soft tissue mass; and was no necrosis, hemorrhage and cystic change; the central part of the lesion may be accompanied by punctate or branching calcifications; in strengthening early stage (arterial phase) obviously even or uneven strengthening of mass, and tumor can be seen as persistent color enhancement by using contrast-enhanced CT. According to the predilection site and imaging features of CD [9][10]，however, UCD needs to be differentiated from several blood rich tumors [11]: thymoma, carotid body tumor, ectopic pheochromocytoma, lymphoma, ectopic chemoreceptor tumors and lymph node metastases.…”

Castleman disease mimicking an aggressive retroperitoneal neoplasm

“…The disease usually presents as a localized soft tissue mass within the neck or mediastinum [2]. Although computed tomography (CT), sonography (US), and angiography findings in this entity have been described [3][4][5][6], the magnetic resonance (MR) findings in Castleman disease are limited to two case reports [7]. No reports describing Castleman disease mimicking a primary retroperitoneal malignancy have been published.…”