Cervical intramedullary schwannoma: a case report and review of the literature

Nicácio, Jardel Mendonça; Rodrigues, José Carlos; Galles, Marcos Henrique Lima; Faquini, Igor Vilela; Pereira, Clemente Augusto de Brito; Ganau, Mario

doi:10.4081/rt.2009.e44

Cited by 28 publications

(29 citation statements)

References 32 publications

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“…1 Intramedullary schwannoma is more frequently found in males than females (male:female = 3:1). 10 The fourth decade of life is the mean age of onset of the symptoms. 11 Pyramidal symptoms manifest most commonly and are followed by sensory disturbances and sphincter malfunction.…”

Section: Discussionmentioning

confidence: 99%

“…7 In some cases, it has been reported that muscular fasciculations were the first clinical manifestation. 10 The time between the beginning of the symptoms until diagnosis was almost always lengthy, with a mean of 28.2 months (range: 6 weeks to 12 years). 7 Intramedullary schwannoma has three types based upon the lesion's location in the cross-sectional area of the spinal cord: central, surfacing, and dumbbell.…”

Section: Discussionmentioning

confidence: 99%

“…To our knowledge, several authors did a literature review of intramedullary schwannomas since We have found that 48 cases were reported since 2005, which brings the total number of cases to 118, including our case. [1][2][3]8,10,11,13,18,19,[23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] The cases reported between 2005 and 2014 are summarized in ►Tables 1 and 2. Lee et al studied 10 cases of intramedullary schwannomas that were diagnosed in their hospital from 1995 to 2010 and they found that 7 of them were in the lumber region and 3 in the cervical regions.…”

Section: Discussionmentioning

confidence: 99%

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Cervical Intramedullary Schwannoma with Syrinx: Case Report and Review of the Literature

Alqarni

Alarifi

Alassiri

et al. 2017

IJNS

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Schwannoma is a nerve sheath tumor originating from the Schwann cell. It is benign in nature and it arises from anywhere where Schwann cells can be found. It is rarely found in the parenchyma of the spinal cord. Intramedullary schwannomas (or neurilemmomas) without evidence of neurofibromatosis are rare spinal cord tumors. Intramedullary schwannoma was first reported in 1932 by Penfield. Our patient presented with neck pain, gradually worsening, weakness in the right upper and lower limbs, numbness in both shoulders, and a decrease in the grasping strength of both hands over a 4-year period. A magnetic resonance imaging of the spine showed a heterogeneously enhancing mass in the cervical spinal cord extending from the C2 to T1 levels with associated hemorrhagic changes. Histologically, the tumor was found to be composed of bland spindle cells with blunt-ended and sometimes wavy nuclei admixed with hyalinized vasculature. Surrounding reactive spinal cord parenchyma with frequent Rosenthal fibers was also observed. Focal Verocay bodies were evident, and with immunohistochemistry, there was diffuse and strong positivity for S100, which is confirmatory for the diagnosis of schwannoma. We report a case of cervical intramedullary schwannoma presented with syringobulbia in a young adult. AbstractKeywords ► intramedullary schwannomas ► syrinx ► spinal cord tumor ► cervical Indian

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Cervical Intramedullary Schwannoma with Syrinx: Case Report and Review of the Literature

Alqarni

Alarifi

Alassiri

et al. 2017

IJNS

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“…Although Kernohan was recognized as the first neurosurgeon to report an IS in 1952, Penfield had reported this in 1932. [ 3 4 ] IS are rare, accounting for 0.3% of all primary spinal cord intramedullary neoplasms. [ 2 ] The most common location for IS is the cervical spine (63%) as in our case, followed by thoracic and lumbar levels.…”

Section: Discussionmentioning

confidence: 99%

Cervical intramedullary schwannoma mimicking a glioma

et al. 2015

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We present a case of a cervical intramedullary schwannoma (IS), which resembled a glioma on radiology. Somatic and root pain, the most common presenting complaints of IS, were lacking in our patient, and the characteristic magnetic resonance finding of an enhancing thickened nerve root in IS, was absent in our case. Preoperative diagnosis of a cervical IS is not always possible. Complete tumor resection is the ideal treatment for IS. Intraoperative frozen section can be a useful for decision making though the tumor-cord plane will ultimately decide if the tumor can be radically excised.

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“…As most of benign tumors, their presence is suspected by the onset of neurological signs in a slow-growing fashion caused by vascular or nervous conflicts. [2620] Spontaneous intracranial hemorrhage occurs in 3.9% of all brain tumors,[27] especially in aggressive ones, such as metastatic tumors or malignant gliomas. Apart from high-vascularized tumors, as choroid plexus papillomas and pituitary adenomas, spontaneous intracranial hemorrhage associated with a benign lesion is an even more uncommon condition.…”

Section: Introductionmentioning

confidence: 99%

Clinical and radiological aspects of cerebellopontine neurinoma presenting with recurrent spontaneous bleedings

Maimone

Ganau²,

Nicassio³

et al. 2013

Surg Neurol Int

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Background:Neurinomas are benign, usually encapsulated, tumors growing in peripheral nerve sheath with a high incidence in the cerebellopontine angle.Case Description:We report a case of vestibular neurinoma (VN) with a “biphasic” pattern of intratumoral hemorrhage presenting with cephalalgia along with progressive ipsilateral mild impairment of both VII and VIII cranial nerves. A thorough preoperative magnetic resonance imaging study better characterized the patchy pattern of the round shaped lesion, resulting in three different intensity signals, due to the peculiar characteristics of the tumoral mass and the recurrent bleedings, respectively. Postoperatively, histological examination confirmed the diagnosis of neurinoma.Conclusion:Hemorrhagic VN are rare tumors; from the first case described in 1974 only 43 more have been reported in the literature so far. Noteworthy, “biphasic” bleedings are even rarer. From an accurate review of the literature we collected and thus emphasized the radiological and clinical features of this rare entity. Eventually, we suggest that the early surgical removal of clots and tumor is essential to provide the best chance of neurological improvement.

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Cervical intramedullary schwannoma: a case report and review of the literature

Cited by 28 publications

References 32 publications

Cervical Intramedullary Schwannoma with Syrinx: Case Report and Review of the Literature

Cervical Intramedullary Schwannoma with Syrinx: Case Report and Review of the Literature

Cervical intramedullary schwannoma mimicking a glioma

Clinical and radiological aspects of cerebellopontine neurinoma presenting with recurrent spontaneous bleedings

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