Cervical lymphadenopathy in children—Incidence and diagnostic management

Niedzielska, G; Kotowski, Michał; Niedzielski, Artur; Dybiec, Ewa; Wieczorek, Paweł

doi:10.1016/j.ijporl.2006.08.024

Cited by 98 publications

(76 citation statements)

References 17 publications

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“…Enlarged, palpable lymph nodes are usually related with reactive hyperplasia in the lymph node tissue in relation with regional inflammatory state (9). Lymphadenopathy occurs following lymphadenitis which occurs most commonly in relation with infections in the childhood (1).…”

Section: Discussionmentioning

confidence: 99%

“…Epitrochlear and supraclavicular lymph nodes require further investigation, since they may be related with malignancy, even if they are smaller than 0.5 cm. In some studies, lymph nodes up to 0.3 cm in the supraclavicular region, 0.5 cm in the axilla, 1 cm in the neck and 1.5 cm in the inguinal region are generally not accepted to be pathological in the childhood (8,9). Lymph nodes smaller than 2 cm were palpated in the neck in 26 of our patients (27%) and lymph nodes smaller than 1 cm were palpated in the axillary region in three of our patient (3%).…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of children with lympadenopathy

et al. 2017

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Aim: To examine children who present with enlargement of lymph nodes in terms of demographic, clinical, serological and radiological aspects. Material and Methods:Ninety-eight patients who presented with a complaint of enlargement of lymph nodes were examined in terms of demographic, clinical, serological and radiological aspects by screening file data retrospectively. The character of lymph nodes (reactive, malign) was evaluated according to the distribution, number, sizes and blood supply determined in ultrasonographic measurements. Fisher's Exact test and Mann-Whitney U Test were used in comparison of the groups. Kappa value was used in assessment of compatibility between the two groups.Results: Cervical lymphadenomegaly was found most frequently in accordance with the complaint of swelling in the neck. Erythrocyte sedimentation rate, ultrasonography, Epstein-Barr virus (EBV) and cytomegalovirus (CMV) IgM were not found to be statistically significatly different between the normal and abnormal physical examination groups (erythrocyte sedimentation rate; p=0.623, USG; p=0.753, EBV and CMV; p=1.00). Cytomegalovirus and EBV IgM were not found to be statistically significatly different between the normal and abnormal ultrasonography groups (CMV; p=0.35, EBV; p=0.36). There was no compatibility between physical examination and ultrasonography (=0.32). Conclusion:Lymphadenopathy is a common problem in the childhood and necessitates a careful physical examination and follow-up. Laboratory and imaging methods should be used when necessary. Although lymphadenopathy is mostly related with infections, care should be taken in terms of malignancy and malignancy should be eliminated. The important point is systemic evaluation and follow-up of the patient. It is important to note physical examination findings and clinical follow-up findings, because frequent ultrasonographic investigations may confuse physicians and families with high values of lymph node measurements despite normal physical examination. Therefore, using our fingertips with a good physical examination is still our most sensitive diagnostic tool instead of ultrasonography. (Türk Ped Arş 2014; 49: 30-5)

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of children with lympadenopathy

et al. 2017

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“…Yorumu yapan radyologa bağlı olması dezavantajı olsa da bilgisayarlı tomografiye ve manyetik rezonans görün-tülemeye (MRG) göre ucuz bir incelemedir. [12] Yüksek çözünürlüklü ve renkli Doppler ultrasonografi reaktif düğümlerinin, enfekte veya iltihaplı düğümlerin kötü huylu lenf düğümlerinin ayrımında yardımcı olabilir.…”

Section: Tanı Yöntemleriunclassified

“…12,13] Bilgisayarlı tomografi veya MRG daha çok lenfadenopati karakterizasyonun tanısı veya cerrahi planlaması için gereklidir. Akciğer grafisi malignite şüp-hesinde düşünülmelidir.…”

Section: Tanı Yöntemleriunclassified

Approach to pediatric cervical lymphadenopathy

Yazıcı¹

2015

KBB Uygulamaları

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ÖZServikal lenfadenopati pediatrik nüfusta yaygın olarak görülür; sağlıklı çocukların yaklaşık %38 ila %45'inde ele gelen lenfadenopati bulunabilir. Esasen, doğru bir insidans vermek zordur çünkü viral üst solunum yolu hastalıklarından sonra görülüp kendini sınırlayan bir patolojidir. Ayırıcı tanısında birçok hastalık olabileceği için ayrıntılı öykü ve fizik muayene doğru tanıyı koymaya yardımcıdır. En sık rastlanan neden enfeksiyondur.Anahtar sözcükler: Servikal; lenfadenopati; pediatrik. ABSTR ACTCervical lymphadenopathy is common in the pediatric population; palpable lymphadenopathy may be present in approximately 38 to 45% of healthy children. In fact, it is difficult to give a true incidence since it is a pathology that is seen after viral upper respiratory diseases and limits itself. Detailed history and physical examination assist in establishing a correct diagnosis since many diseases may be involved in its differential diagnosis. The most common cause is infection.

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“…Although the most common cause is conventionally accepted to be congenital lesions, some authors suggest that reactive lymphadenopathies (LAP) that develop following viral and bacterial infections are the most common cause (4,5). The final diagnosis is established through pathological examination after excision, but fine needle aspiration biopsy (FNAB) from the mass can be performed for pre-diagnosis (6). In the studies conducted in USA over the past 20 years, it has been reported that the results of FNAB in pediatric cases are as correct as those in adult patients and FNAB protects patient from negative outcomes such as general anesthesia, pain, scar, wound infection, and delayed diagnosis (7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Pediatric Mass Lesions of the Head and Neck Region and Fine-Needle Aspiration Biopsy Results

Eskı¹,

Akdoğan²,

Türkoğlu³

et al. 2016

Turk Arch Otorhinolaryngol

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Objective: 1. To provide a classification of pediatric mass of the head and neck region and evaluate their frequency. 2. To examine the findings of fine-needle aspiration biopsy (FNAB) in pediatric patients along with its contribution to diagnosis. Methods:Totally, 233 pediatric patients (125 boys and 108 girls) operated at Başkent University for head and neck mass were included. Clinical, radiological, and histopathological data were retrieved from medical records. Results:The mean age was 119±65 months, and the mean duration of follow-up was 75±49 months. Localization of the masses was as follows: 208 (89%) in the neck, 21 (9%) in the oral cavity, 2 (1%) in the neck and nasopharynx, and two (1%) in the larynx. The most common surgical procedure was open excisional biopsy (n=105, 45%) followed by cystic mass excision (n=72, 31%) and salivary gland excision (n=33, 14%). Based on histopathological findings, benign cystic lesions were the most common disease group (n=77, 33.1%), whereas reactive lymphadenopathy was the most common condition (n=36, 15%) when a single disease was considered. Infectious/inflammatory diseases, malignancies, and benign salivary gland diseases were present in 49 (21%), 24 (10.3%), and 22 (9.4%) patients, respectively. FNAB was performed in 29.8% of the patients with an accuracy of 90.3% (95% CI, 80.1-96.4). Conclusion:The differential diagnosis of head and neck masses during childhood includes a wide spectrum with the different conditions being benign cystic diseases of congenital origin and reactive lymphadenopathies. Owing to its high predictive value, FNAB represents a rapid and reliable method that can be commonly used in both adult and pediatric patients.

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Cervical lymphadenopathy in children—Incidence and diagnostic management

Cited by 98 publications

References 17 publications

Evaluation of children with lympadenopathy

Evaluation of children with lympadenopathy

Approach to pediatric cervical lymphadenopathy

Pediatric Mass Lesions of the Head and Neck Region and Fine-Needle Aspiration Biopsy Results

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