Cervical neoplasia in pregnancy. Part 1: screening and management of preinvasive disease

Hunter, Mark; Monk, Bradley J.; Tewari, Krishnansu S.

doi:10.1016/j.ajog.2008.04.010

Cited by 70 publications

(67 citation statements)

References 61 publications

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“…La prevalencia de citologías cervicales anormales durante el embarazo detectada en nuestro estudio fue del 14,4%, siendo mayor a lo reportado en la literatura (5-8%), así como la incidencia de CaCu invasor 0,8% (0,1-0,02%) (7,11). Existen reportes de que las displasias diagnosticadas durante el embarazo, presentan regresión entre el 10-70%, la persistencia de la severidad se reporta en el 25-47% y la progresión ocurre en el 3-30% de los casos (4,11).…”

Section: Discussionunclassified

“…Las intervencio- nes diagnósticas como la colposcopia deben realizarse por personal altamente capacitado, ya que los cambios fisiológicos asociados al embarazo pueden dificultar el diagnóstico (4,8) La biopsia de lesiones sospechosas es una intervención necesaria y aceptable y debe realizarse bajo visualización colposcópica. El inicio del tratamiento del carcinoma invasor del cérvix debe basarse en la edad gestacional al momento del diagnóstico (7,9,10).…”

Section: Discussionunclassified

“…El pico máximo de incidencia del carcinoma cervical in situ ocurre entre los 25 y 35 años, mientras que la incidencia del CaCu aumenta después de los 40 años (6,7). Se ha observado que tanto el estadio, el curso y el pronóstico del CaCu en pacientes embarazadas son similares a las no embarazadas (4,8).…”

Section: Introductionunclassified

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Prevalencia De Displasia Cervical en Embarazadas en El Hospital Universitario De Monterrey, Nuevo León, México

Acosta¹,

Gutiérrez²,

Rodríguez³

et al. 2010

Rev. chil. obstet. ginecol.

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RESUMENObjetivo. Determinar la prevalencia de displasia cervical en mujeres embarazadas. Método. Estudio observacional, longitudinal, prospectivo, en el cual se analizaron los resultados de 250 pacientes embarazadas que acudieron a control prenatal en el Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, México, en el período enero 2007 a julio de 2008. Resultados. Se analizaron 36 citologías anormales (14,4%), las cuales reportaron ASCUS 3,2% (n=8), LIEBG 8% (n=20), LIEAG 2,4% (n=6) y CaCu 0,8% (n=2). La prevalencia de displasia cervical confirmada por biopsia fue 5,6% (n=14). Conclusiones. Se recomienda realizar la citología cervical a toda paciente embarazada, para la detección y tratamiento oportuno de las displasias cervicales.PALABRAS CLAVE: Citología cervical, displasias cervicales, cáncer cérvicouterino, embarazo, control prenatal SUMMARYObjective. To evaluate the prevalence of cervical dysplasia among pregnant women. Method. We conducted an observational, longitudinal, prospective study, that analyzed the results of 250 cervical smears of pregnant patients that attended the Obstetrics consult of the University Hospital in Monterrey, Mexico, between January 2007 and July 2008. Results: 36 abnormal smears were analyzed (14.4%). Showing ASCUS in 3.2% (n=8), LSIL in 8% (n=20), HSIL in 2.4% (n=6) and AIS in 0.8% (n=2). The prevalence of cervical dysplasia confirmed by biopsy was 5.6% (n=14). Conclusions: We recommend performing cervical smears to all pregnant women for detection and appropriate treatment of cervical dysplasia.

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Section: Discussionunclassified

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Prevalencia De Displasia Cervical en Embarazadas en El Hospital Universitario De Monterrey, Nuevo León, México

Acosta¹,

Gutiérrez²,

Rodríguez³

et al. 2010

Rev. chil. obstet. ginecol.

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“…Por ejemplo, entre los 4 millones de mujeres que anualmente se embarazan en los Estados Unidos, entre el 2 a 7% tienen una citología anormal durante el embarazo, de las cuales solo en 1,5 a 12 de cada 100.000 embarazos se complican por el diagnóstico de una neoplasia cervical (18).…”

Section: Discussionunclassified

Cáncer Cérvico-Uterino Asociado Al Embarazo: Reporte De Un Caso

Machado

Zambrano

Benítez

2009

Rev. chil. obstet. ginecol.

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RESUMENLa asociación entre cáncer y embarazo es infrecuente, con una incidencia entre 0,02-0,1%. El cáncer cérvico-uterino es la neoplasia más frecuentemente asociada a la gestación, con tasas entre 1-13/10.000 partos. Se presenta el caso de una gestante indígena de 38 años de edad y 15 semanas de gestación, con el diagnóstico de un carcinoma de cuello uterino epidermoide de células grandes, estadio clínico IIB. PALABRAS CLAVE: Cáncer cérvico-uterino, embarazo SUMMARYThe association between cancer and pregnancy is infrequent, with an incidence between 0.02-0.1 percent. Cervical cancer being the most frequently neoplasia associated to the gestation, with rates between 1-13/10,000 childbirths. We report the case of an indigenous pregnant of 38 years old and 15 weeks of gestation, with the diagnoses of cervical cancer of great cells, clinical stage IIB.

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“…The regression rate of these lesions was not followed up in this study, however, the Zaria study showed a regression rate of 50%. Studies done on course of preinvasive cervical lesion in developed countries showed surprisingly high rate of regression from HGSIL to LGSIL and from LGSIL to negative smears during pregnancy and delivery [15].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Pattern of Abnormal Pap Smear among Pregnant Women Attending Antenatal Clinic in a Missionary Hospital in Abakaliki, Southeast Nigeria

Ekwedigwe¹,

Ezeonu²,

Edegbe³

et al. 2018

OJOG

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BACKGROUND: Cervical cancer is the most common type of cancer affecting the genital tract among women in developing countries. Screening programmes have been well talked about in Nigeria, but they are not well organized. Hence, the incidence of cervical cancer does not appear to be reducing. A possible way of solving this problem is by doing an opportunistic pap smear among women attending antenatal clinics, since a good number of women do access antenatal care. OBJECTIVES: To determine the prevalence, knowledge, awareness, practice, risk factors and pattern of Pap smear among women attending antenatal clinic in Mile 4 hospital, Abakaliki. METHOD: This is a cross-sectional study carried out at the antenatal clinic of Mile 4 Hospital, Abakaliki, Nigeria. A total of 110 consecutive pregnant women who fulfilled the inclusion criteria and have given their consent were recruited into the study at the time of their first prenatal (booking clinic) visit for antenatal care. Data was collected using a questionnaire. Conventional Papanicolaou smear was taken using the standard procedure. The cytopathologic findings were documented in the questionnaire. RESULTS: Out of the 110 pregnant women who had cervical cytology by Pap smear, 7 had pre-invasive cervical lesion, giving a prevalence rate of 6.3%; 5 (71.4%) were low-grade squamous intraepithelial lesion (LGSIL) while 2 (28.6%) were high-grade squamous intraepithelial lesion (HGSIL). Fifty women (45.5%) had negative smears. Inflammatory smears were seen in 50 women (45.5%). Insufficient smear was seen in 3 women (2.7%). Fifty-six women had knowledge about cervical canHow to cite this paper: Ekwedigwe, K.C., Ezeonu, P.O., Edegbe, F., Esike, C., Agbata, A.T., Ukaegbe, C. cer (50.9%), while thirty-six women (32.7%) were aware of a screening program for cervical cancer and only 2 women (1.8%) had been screened in the past. Hence, from this study, the population screening rate was approximately 2%. The risk factors were age of coitarche <15 years, number of sexual partners, previous history of sexual transmitted infection, genital warts, human immune deficiency virus and use of contraceptives. CONCLUSION: The pap-smear findings among pregnant women in Abakaliki, Nigeria showed that the pre-invasive lesion of the cervix is relatively common. Pap smear should be made routine for all pregnant women.

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Cervical neoplasia in pregnancy. Part 1: screening and management of preinvasive disease

Cited by 70 publications

References 61 publications

Prevalencia De Displasia Cervical en Embarazadas en El Hospital Universitario De Monterrey, Nuevo León, México

Prevalencia De Displasia Cervical en Embarazadas en El Hospital Universitario De Monterrey, Nuevo León, México

Cáncer Cérvico-Uterino Asociado Al Embarazo: Reporte De Un Caso

Prevalence and Pattern of Abnormal Pap Smear among Pregnant Women Attending Antenatal Clinic in a Missionary Hospital in Abakaliki, Southeast Nigeria

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