Cervical Ripening and Labor Induction and Augmentation, 5th Edition

Simpson, Kathleen Rice

doi:10.1016/j.jogn.2020.04.005

Cited by 4 publications

(7 citation statements)

References 138 publications

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“…According to Wei et al, dinoprostone was superior to oxytocin for cervical ripening with a lower rate of cesarean delivery in pregnant women with the Bishop score of 0–3, but both agents had a similar outcome for group with the Bishop score of 4–6 37 . Thus, before using oxytocin augmentation, promptly cervical ripening with dinoprostone can increase the success rate of induction of labor 5,27 . In our study, 39 pregnant women received an adjunctive low‐dose oxytocin infusion.…”

Section: Discussionmentioning

confidence: 62%

“…At this time, if Bishop's score was greater than 5 or the cervical dilation was found to be superior than 2 cm on digital examination without significantly uterine contractions. A low‐dose oxytocin intravenous administration (starting dose at 2 mUI/min, increased 2 mUI/min every 30 min until achieving three contractions/10 min) was added within at least 6 h for augmentation in order to shorten the cervical ripening, at least 30 min interval between dinoprostone removal and initiation of oxytocin 5,22 . Then, the patient was immediately transferred to the delivery room for continuous monitoring.…”

Section: Methodsmentioning

confidence: 99%

“…37 Thus, before using oxytocin augmentation, promptly cervical ripening with dinoprostone can increase the success rate of induction of labor. 5,27 In our study, 39 pregnant women received an adjunctive low-dose oxytocin infusion. These cases had an evaluation of the Bishop score >5 after DCR.…”

Section: Oxytocin Administrationmentioning

confidence: 99%

“…Among them, prostaglandin E2 (PGE 2) and transcervical balloon contribute to pre-induction cervical ripening and play an important role to prepare the unfavorable cervix before the augmentation of oxytocin. 5 Some studies have mentioned the effect of foley catheters and PGE 2 with controversial results. [6][7][8][9] The mechanical procedure can increase the infectious risk and the anxiety of the patient, more frequently requiring additional interventions such as oxytocin augmentation and amniotomy.…”

Section: Introductionmentioning

confidence: 99%

“…Generally, a variety of agents has been described to ripen the cervix in the literature. Among them, prostaglandin E2 (PGE 2) and transcervical balloon contribute to pre‐induction cervical ripening and play an important role to prepare the unfavorable cervix before the augmentation of oxytocin 5 . Some studies have mentioned the effect of foley catheters and PGE 2 with controversial results 6–9 .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Nguyen

Vuong

Nguyen

et al. 2023

J of Obstet and Gynaecol

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The study purposed to evaluate the success rate of cervical ripening using dinoprostone controlled-release vaginal insert and reveal some factors relating to successful cervical ripening. Methods: This cross-sectional study was conducted at Tu Du Hospital in Vietnam from December 2021 to August 2022. The study enrolled 200 pregnant women with gestational age ≥37 weeks diagnosed with oligohydramnios. These candidates underwent dinoprostone cervical ripening (DCR) according to the local protocol. The Bishop score ≥7 after 24 h was determined for the successful cervical ripening (SCR). Results: In total, the success rate of DCR achieved at 57.5% and the cesarean delivery rate was 46.5%. None of the severe side-effects and complications was present. Using multivariable logistic regression, the study found that the body mass index ≥25 kg/m 2 and oxytocin infusion drip related to SCR with adjusted odds ratio (aOR): 3.67 (95% confidence intervals [CI]: 1.78-7.57) and aOR: 4.68 (95% CI: 1.84-11.93), p < 0.001. Using the Kaplan-Meier curve, the present study revealed a significant difference between Bishop <3 and ≥3 following the duration time of cervical ripening, with hazard ratio: 1.38 (95% CI: 1.19-1.59), p < 0.001. The time duration of cervical ripening was not significantly different following amniotic fluid index from 3 to 5 cm. Conclusions: Cervical ripening using a dinoprostone vaginal insert is a potentially acceptable method in term pregnancy accompanying with oligohydramnios. The probability of SCR can be predicted on a careful assessment of relative factors by obstetricians. Further studies are required to strengthen these findings.

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Section: Discussionmentioning

confidence: 62%

Section: Methodsmentioning

confidence: 99%

Section: Oxytocin Administrationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Nguyen

Vuong

Nguyen

et al. 2023

J of Obstet and Gynaecol

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Moving preinduction cervical ripening to a lower acuity inpatient setting using the synthetic hygroscopic cervical dilator: a cost-consequence analysis for the United States

Saunders

Grisamore

Wong³

et al. 2022

Journal of Medical Economics

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Different expressions of aquaporin water channels and macrophages infiltration in human cervix remodeling during pregnancy

Yang¹,

Yu²,

Zhang³

et al. 2021

Biology of Reproduction

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Despite aquaporin water channels (AQPs) play a critical role in maintaining water homeostasis in female reproductive tract and prompt a gradual increase in water content in cervical edema as pregnancy progressed, their relationship with macrophage infiltration and collagen content in human cervical remodeling need to be further investigated. This is the first study to examine the expression and localization of AQP3, AQP4, AQP5, AQP8 and macrophages simultaneously in human cervical ripening. The immunoreactivity of these AQPs was 2.6 to 6-fold higher on gestational weeks 26 (GD26W) than that on GD6W and GD15W, but AQP4 expression on GD39W dropped a similar extent on GD15W, other AQPs continued to rise on GD39W. The AQP3, AQP4 and AQP5 intensity seemed more abundant in cervical stroma than in the perivascular area on GD26W; the distribution of AQP3, AQP5 and AQP8 in cervical stroma was equivalent to that in the perivascular area on GD39W. Macrophage numbers were 1.7-fold higher in subepithelium region and 3.0-fold higher in center area on GD26W than that on GD15W; such numbers remained elevated on GD39W. The electron micrographs showed that cervical extensibility increased significantly on GD26W and GD39W accompanied with increased macrophage infiltration, cervical water content and much more space among collagen fibers. These findings suggest that the upregulation of AQPs expression in human cervix is closely related to enhanced macrophage infiltration during pregnancy; there may be a positive feedback mechanism between them to lead the increase of water content and the degradation of collagen.

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Cervical Ripening and Labor Induction and Augmentation, 5th Edition

Cited by 4 publications

References 138 publications

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Moving preinduction cervical ripening to a lower acuity inpatient setting using the synthetic hygroscopic cervical dilator: a cost-consequence analysis for the United States

Different expressions of aquaporin water channels and macrophages infiltration in human cervix remodeling during pregnancy

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