CFD simulation of the inactivation of Geobacillus stearothermophilus on dental handpieces

Feurhuber, Manuel; Burian, Paul; Magno, Marino; Miranda, Marco; Hochenauer, Christoph

doi:10.1016/j.ijheatmasstransfer.2019.118649

Cited by 11 publications

(3 citation statements)

References 35 publications

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“…A single measurement is insufficient to predict the real concentration of NCGs present in the steam, requiring more than one collection to estimate the actual amount of NCGs. Currently, other methodologies are being proposed to obtain more precise values, such as Computational Fluids Dynamics (CFD) studies [12][13][14] or even applying mathematical models based on temperature and pressure measurements inside the sterilizers. In this study, the data collection is connected to the steam supply pipe for the sterilizers, making it difficult to insert temperature and pressure sensors to apply such methods.…”

Section: Discussionmentioning

confidence: 99%

“…be a useful tool to investigate the various physical phenomena that occurs within steam sterilizers, as predicting steam condensation in the presence of NCGs [13], the air-removal process during the pre-sterilization phase of both vacuum and non-vacuum steam sterilization cycles and the inactivation of Geobacillus stearothermophilus on real dental handpieces [14].…”

Section: Plos Onementioning

confidence: 99%

“…The CFD model developed was able to predict the volume fraction of NCGs, as well as steam penetration inside the steam sterilizer, including the hollow loads. CFD simulations can be a useful tool to investigate the various physical phenomena that occurs within steam sterilizers, as predicting steam condensation in the presence of NCGs [ 13 ], the air-removal process during the pre-sterilization phase of both vacuum and non-vacuum steam sterilization cycles and the inactivation of Geobacillus stearothermophilus on real dental handpieces [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

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Analysis of water quality over non-condensable gases concentration on steam used for sterilization

Miguel¹,

Laranjeira²,

Ishii

et al. 2022

PLoS ONE

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Background Non-condensable gases (NCGs) are all gases that do not undergo liquefaction during the saturated steam sterilization process. During a sterilization cycle, the NCGs presence inside the chamber is one of the biggest threats to the sterilization process compromising process validation and product quality. Methods In this work, 170 testing of NCGs concentrations performed between September 2016 and August 2021 were carried out by Orionce Serviços de Metrologia Ltda (Barueri, SP, Brazil), according to EN285:2015 procedure. For steam generation, the types of water used were softened water (SW), one-step reverse osmosis (RO), purified water (PW), and water for injection (WFI). The data obtained were analyzed using Minitab® software, version 18.1, to identify a relationship between the water quality used for steam generation and the concentration of non-condensable gases determined into equipment qualification. Findings From total tests performed, 109 tests passed, and 61 tests failed, representing 64.2% and 35.8%, respectively. A higher failure rate was observed in terms of concentration of non-condensable gases in systems that used purified water for steam generation (64.7%), followed by softened water (55.6%), one-step reverse osmosis (42.9%), and water for injection (7.6%). Conclusion System processes using WFI for steam generation showed better results for steam quality approvement, in terms of NCGs concentration, compared to softened, purified, or reverse osmosis water treatments in the concentration of non-condensable gases in steam used for sterilization processes of industrial utilities.

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Section: Discussionmentioning

confidence: 99%

Section: Plos Onementioning

confidence: 99%