Abstract:Fluorochrome-labelled iron oxide magnetic nanoparticles (MNP) have been of great help in elucidating biological processes. Here, we used dually-fluorochrome-labelled MNP and studied to what extent fluorescence detection could reflect their fate in living animals. One day after application in mice (200 µmol Fe/kg body weight), the fluorescence of the dye attached to the core (DY-730) was very prominent and in agreement with the increase of iron in the liver and spleen of mice, but inconspicuous at time points t… Show more
Among conventional cancer therapies, radio-frequency magnetic hyperthermia (MHT) has widely been investigated for magnetic nanoparticles (MNPs). However, majority of in vivo biodistribution studies have tested very low MNP dosages (equivalent...
Among conventional cancer therapies, radio-frequency magnetic hyperthermia (MHT) has widely been investigated for magnetic nanoparticles (MNPs). However, majority of in vivo biodistribution studies have tested very low MNP dosages (equivalent...
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