Change in Domains that Influence Quality of Life after Major Lower Limb Amputation in Patients with Peripheral Arterial Disease

Silva, Joana Cruz; Oliveira, Vânia Constâncio; Lima, Pedro; Correia, Mafalda; Moreira, Mario E.; Anacleto, Gabriel

doi:10.1016/j.avsg.2021.01.082

Cited by 7 publications

(15 citation statements)

References 33 publications

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“…Majority of our patients did not have a prosthesis even 2 years post amputation, in contrast to other literature where patients received prosthesis by 14 months 27 . Poverty and rehabilitation center accessibility constituted major factors for avoiding prosthesis and ultimately affecting HRQOL.…”

Section: Discussioncontrasting

confidence: 83%

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Hashim¹,

Zarmina²,

Panhwar³

et al. 2023

PJMHS

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Aim: To assess domains of health-related quality of life among patients undergoing major lower limb amputation secondary to peripheral arterial disease. Study design: Observational questionnaire-based study. Place and Duration: Data from 1st January to 31 December 2020(collected from September 2022 to November 2022) was assessed out of which ninety-one patients fulfilled the inclusion criteria. Methodology: Twenty-three patients were interviewed after verbal consent over telephone using validated questionnaires: World Health Organization Quality of Life-BREF, Amputee Single Item Mobility Measure, Locomotor Capability Index-5. Independent sample t-tests and ANOVA were performed for demographics and domain scores. Pearson-Correlation tests were performed for relations between domains and mobility scores. Results: 12 (52.20%) of interviewed patients received below knee amputation, comprising mostly of males 16 (69.60%) with diabetes 18 (78.30%). Participants who used prosthesis had statistically significantly greater mobility scores compared to non-prosthesis users t(21)=3.396, p=0.03. Below knee amputees report better quality of life compared to above knee as these amputees had lower physical domain (mean difference -22.75, p=0.027) and environmental domain scores (mean difference -12.44, p=0.009). This study found that male participants had statistically significantly greater physical t(21)=2.698, p=0.013 and environmental t(21)=2.77,1 p =0.011 scores after a major lower limb amputation compared to females. Conclusion: Males and patients with prosthesis report significantly better quality of life compared to females and non-prosthesis users, owing to socioeconomic and cultural barriers. Keywords (MeSH): Amputation, Surgical, peripheral arterial disease, Artificial Limbs, Quality of Life

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Section: Discussioncontrasting

confidence: 83%

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Hashim¹,

Zarmina²,

Panhwar³

et al. 2023

PJMHS

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“…Characteristics of each instrument are shown in Supplemental Table 3 (Table, Supplemental Digital Content 2, Supplemental Table 3, http://links.lww.com/SLA/D911). Sixteen of these instruments were used in 103 studies25–30,32–40,42–44,46–52,54–79,81,82,84–93,97–108,110–118,120–128,130–138,157 on QOL outcomes and CUA. These studies were conducted across 23 countries and published between 1992 and 2021.…”

Section: Resultsmentioning

confidence: 99%

“…There were 97 studies25–29,32,33,35–40,42–44,46–52,54–62,64–70,72–79,81,82,84–93,97–102,104–108,110–118,120–128,130–132,134–138,157 reporting QOL outcomes in CLTI patients (Table, Supplemental Digital Content 3, Supplemental Table 4, http://links.lww.com/SLA/D912). VascuQoL-25 was the most common disease-specific instrument used (n=17).…”

Section: Resultsmentioning

confidence: 99%

“…Of 6470 records identified in the primary database search, 114 studies25–138 were included. An additional 16 studies139–154 were included from the secondary database search and 16 studies155–170 from the reference list search.…”

Section: Resultsmentioning

confidence: 99%

“…There were 97 studies [25][26][27][28][29]32,33,[35][36][37][38][39][40][42][43][44][46][47][48][49][50][51][52][54][55][56][57][58][59][60][61][62][64][65][66][67][68][69][70][72][73][74][75][76][77][78][79]81,82,[84][85][86][87]…”

Section: Studies On Quality Of Life and Cost-utility Analysismentioning

confidence: 99%

See 2 more Smart Citations

Measuring Quality of Life in Chronic Limb-threatening Ischemia Patients and Informal Carers: A Scoping Review

et al. 2022

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Objective: To review quality of life (QOL) instruments for chronic limb-threatening ischemia (CLTI) patients and informal carers, and their use in QOL and cost-utility analysis (CUA) studies. Background: CLTI is a global health problem with significant morbidity affecting patients and informal carers. QOL is increasingly measured for holistic outcomes assessment and CUA. However, measurement instruments in CLTI are poorly understood. Methods: MEDLINE, EMBASE, PsycINFO, CINAHL, COSMIN, PROQOLID, CEA registry, and NHS EED databases were searched for all English language studies up to May 2021. Features of instruments, evidence of measurement property appraisal, and trends in use were assessed. Prospective protocol registration (Open Science Framework: https://doi.org/10.17605/OSF.IO/KNG9U). Results: A total of 146 studies on QOL instruments (n=43), QOL outcomes (n=97), and CUA (n=9) were included. Four disease-specific QOL instruments are available for lower extremity arterial disease (intermittent claudication or CLTI). VascuQoL-25 and VascuQoL-6 have been used in CLTI. There is no CLTI-specific instrument. Of 14 generic instruments, SF-36, EQ-5D-3L, NHP, and WHOQOL-BREF were most common. Studies reporting partial measurement property appraisal favored VascuQoL-25, VascuQoL-6, and SF-36. Feasibility considerations include mode of administration and responder burden. None of 4 available carer-specific instruments have been used in CLTI. Since 1992, the number of QOL studies has increased considerably, but CUA studies are scarce. Informal carers have not been assessed. Conclusions: This review provides a comprehensive reference for QOL measurement in CLTI that helps end-users with instrument selection, use, and interpretation. However, a CLTI-specific instrument is needed. There is an opportunity to benefit society through future CUA studies and evaluation of QOL in informal carers.

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Health-Related Quality of Life Outcomes for Endovascular and Open Surgical Interventions in Aortoiliac and Femoropopliteal Steno-Occlusive Arterial Disease

Tun

Lam²,

Akhtar³

et al. 2022

Patient Reported Outcomes and Quality of Life in Cardiovascular Interventions

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Change in Domains that Influence Quality of Life after Major Lower Limb Amputation in Patients with Peripheral Arterial Disease

Cited by 7 publications

References 33 publications

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Measuring Quality of Life in Chronic Limb-threatening Ischemia Patients and Informal Carers: A Scoping Review

Health-Related Quality of Life Outcomes for Endovascular and Open Surgical Interventions in Aortoiliac and Femoropopliteal Steno-Occlusive Arterial Disease

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