ObjectivesTo better understand the characteristics of migrant workers with pneumoconiosis in China, and the factors that contribute to their morbidity.DesignA cross-sectional study.SettingThis study was conducted in Shanghai, Nanning and Shenzhen, China, between December 2020 and December 2021.ParticipantsThere were 601 questionnaires that were analysed involving 198 migrant workers with pneumoconiosis, 205 workers with pneumoconiosis in state-owned enterprises (SOEs) and 198 other migrant workers with non-pulmonary occupational diseases.Outcome measuresEpidemiological characteristics of pneumoconiosis among migrant workers were determined. Using logistic regression, we examined the factors related to the morbidity of pneumoconiosis in migrant workers.ResultsThe response rate was 93.27%. In comparison with pneumoconiosis among SOE workers, the number of migrant workers with pneumoconiosis who first encountered dust exposure between the ages of 30 and 44 years and had an accumulated dust exposure of 1–10 years was proportionately greater. Migrant workers who developed pneumoconiosis between 18 and 32 years and those who had stage III pneumoconiosis were proportionately greater (p<0.05). Compared with migrant workers with non-pulmonary occupational diseases, six factors were associated with the morbidity of pneumoconiosis in migrant workers. Risk factors were dust exposure (OR=499.25, 95% CI: 68.33 to 3647.59) and someone smoking in the workplace (OR=5.67, 95% CI: 2.18 to 14.78). Protective factors were regular sleeping hours per night, (OR=0.23, 95% CI: 0.09 to 0.60), excellent ventilation (OR=0.09, 95% CI: 0.01 to 0.65), rules and regulations (OR=0.22, 95% CI: 0.07 to 0.66) and post-departure medical examinations (OR=0.24, 95% CI: 0.09 to 0.63).ConclusionsCompared with SOE workers with pneumoconiosis, migrant workers are exposed to dust at an earlier age, but for shorter duration, display morbidity at an earlier age and have a higher proportion of tertiary pneumoconiosis. They are predominantly male and have inadequate employment stability and medical insurance. Occupational health check-ups and management systems are inadequate.