Objective: Negative reinforcement models suggest that negative affect should predict event-level substance use, however, supporting daily-life evidence is lacking. One reason may be an emphasis in ecological momentary assessment (EMA) research on use behavior, which is subject to contextual and societal constraints that other substance outcomes, such as craving, may not be subject to. Therefore, the present study tested momentary, within-person reciprocal relations among negative affect and craving for alcohol and cannabis in daily life. Method: Adults (N = 48) completed 60 days of EMA, consisting of four daily reports spanning 7 a.m.-11 p.m. assessing current negative affect and alcohol/cannabis craving. Preregistered analyses used dynamic structural equation modeling to test whether (a) within-person increases in negative affect co-occurred with within-person increases in alcohol and cannabis craving, and (b) within-person increases in negative affect predicted later within-person increases in craving (and vice versa), and (c) relations differed by substance use frequency. Results: Within-person increases in negative affect were contemporaneously associated with within-person increases in alcohol and cannabis craving. However, increases in negative affect did not prospectively predict increases in craving, and within-person increases in craving did not prospectively predict within-person increases in negative affect. Within-person relations were not moderated by substance use frequency. Conclusions: Negative affect and craving were associated in community adults. However, results advance a growing body of EMA work suggesting that the association of daily-life negative affect and substance use is, at best, not straightforward. Careful attention is needed to better translate existing negative reinforcement theory to the realities of daily life.
Public Health Significance StatementNegative reinforcement models of addiction suggest that negative affect should predict event-level substance use, however, supporting daily-life evidence is lacking, potentially due to an emphasis on use behavior, which is subject to contextual and societal constraints that other substance outcomes, such as craving, may not be subject to. Findings from the present study, however, suggest that within-person increases in negative affect were contemporaneously associated with within-person increases in alcohol and cannabis craving, but were not prospectively linked to one another throughout the day. Findings advance a growing body of EMA work suggesting that the association of daily-life negative affect and substance use is, at best, not straightforward, and careful attention is needed to better translate existing negative reinforcement theory to the realities of daily life.