Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery

Abstract

This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively ( P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.

Visual Acuity Inadequately Reflects Vision-Related Quality of Life in Patients After Macula-Off Retinal Detachment Surgery

“…Micropsia was perceived by the majority of patients with aniseikonia, which confirms earlier findings. 6,13 However, the prevalence of aniseikonia in the current study was somewhat lower than in earlier studies. Okamoto et al 6 and Murakami et al 13 reported a prevalence of 61% and 58% in macula-off RRD patients.…”

“…6,13 However, the prevalence of aniseikonia in the current study was somewhat lower than in earlier studies. Okamoto et al 6 and Murakami et al 13 reported a prevalence of 61% and 58% in macula-off RRD patients. Both studies found abnormalities in patients with aniseikonia, which included subretinal fluid and macular hole.…”

“…Identifying associations between postoperative visual function and quality of life can contribute to a better understanding of how macula-off RRD affects a patient's well-being. Particularly postoperative metamorphopsia and aniseikonia would be of additional value considering the high prevalence of 64% to 89% 4,7,8,12 and 58% to 61%, 6,13 respectively.…”

Impact of the COVID-19 pandemic on characteristics of retinal detachments: the Canadian experience

“… 4 , 6 Patients often experience debilitating micropsia in the affected eye, even in cases with significant improvement in the final corrected distance visual acuity (CDVA) after surgery, which may affect depth perception and binocularity. 7 …”

“…Several studies have demonstrated that the retinal outer segment layer is reduced by approximately 10% of normal width with complete loss of cone photoreceptor markers within 1 week after detachment, with significant changes to the ganglion cell layer. 7 , 8 Duration of the macular detachment, bullous configuration, and CDVA at presentation are several factors that correlate with final CDVA in macula-off detachments. 4 , 5 , 6 …”