Changes in Cardiac Lipids of Chicks Fed Rapeseed Oils With Different Levels of Erucic Acid

Kramer, J. K. G.; Hulan, H. W.

doi:10.4141/cjas77-038

Cited by 5 publications

(7 citation statements)

References 9 publications

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“…In general, the data on total cardiac lipids presented here concur with and confirm the observations of Kramer and Hulan (1977) in that higher levels of lipids were demonstrated gravimetrically in the hearts of chickens fed RSO high in 22:1 compared to those fed the control diet or diets containing either soybean oil or RSO's low in 22:1. However, the lipid content of heart of chickens fed RSO's low in 22:1 was no different from chickens fed the control diet or the diet containing soybean oil.…”

Section: Discussionsupporting

confidence: 92%

“…The data presented here indicate the relative abundance at 4 weeks of both long-chain monoenes, 20:1 and 22:1, in cardiac lipids of chickens fed RSO, confirming the findings of Kramer and Hulan (1977). The results presented also provide evidence of a linear relationship between the dietary levels of these acids (20:1 and 22:1) and their relative concentration in cardiac lipids.…”

Section: C Q Csupporting

confidence: 92%

“…Of interest, however, was the significantly lower cardiac lipids observed at 12 weeks in chickens fed the diet containing Regular RSO (30.66% 22:1) and the high cardiac lipids observed at 16 weeks in chickens fed the control diet. The sucrose in the control diet in the current study served as a ready source of energy and permitted the de novo synthesis of cardiac lipids, whereas in the previous study (Kramer and Hulan, 1977), when the control diet was fed, a large portion of dietary energy had to be derived from soybean meal. Also, the chicks used in the study of Kramer and Hulan (1977) were of a highly inbred line of SCWL, whereas in the current study, a commercial line of SCWL was used and …”

Section: Discussionmentioning

confidence: 96%

“…Probably, as suggested earlier (Kramer and Hulan, 1977), chickens metabolize 20:1 and 22:1 fundamentally differently from rats. This, coupled with the differences in fat absorption known to exist between the rat and the chicken (fat absorption in the albino rat is via the lymphatics, whereas in the chicken it is via the portal system to the liver) and the rate of fatty acid utilization, may play an important role in protecting the chicken from myocardial damage.…”

Section: C Q Cmentioning

confidence: 88%

“…In ducklings, erucic acid produces a hydropericardium and leads to a rapid increase in mortality (Abdellatif and Vies, 1970). When poultry are fed diets containing RSO high in 20:1 and 22:1, these fatty acids are deposited in body fats (Salmon, 1969a,b;Kramer and Hulan, 1977). Although fairly large amounts of both these fatty acids accumulated in the cardiac lipids of chicks fed diets containing RSO, Lall et al (1972) found no lesions in the myocardium attributed to RSO feeding.…”

Section: Introductionmentioning

confidence: 99%

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Growth, Heart Weight, Cardiac Lipid, and Pathology of Chickens Fed Soybean Oil or Oil Extracted from Different Rapeseed Cultivars

Hulan¹,

Corner²,

Nash³

et al. 1982

Poultry Science

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A total of 384 male Single Comb White Leghorn chicks of the Hyline strain were randomized in 24 Petersime battery units of 16 birds per unit. Four replicate pens were fed either a basal (control) diet containing no added oil or a diet supplemented with 20% by weight of either soybean oil or rapeseed oil (RSO) from cultivars Tower, Candle, Regular, or R-500. Levels of crucic acid (22:1) in the RSO's ranged from .1 to 51.6%. Four birds from each unit were killed at 4, 8, 12, and 16 weeks for cardiac lipid analysis and pathology. Feeding RSO had no consistent effect on body weights, heart weights, or the heart-to-body weight ratio. Only the diet containing R-500 (51.6% 22:1) consistently increased cardiac lipid levels as measured gravimetrically. Maximum deposition of the long-chain monoenes (22:1) and eicosenoic acids (20:1) occurred in the cardiac lipids by 8 weeks, and the levels remained high throughout the 16-week trial. The relative concentration of these long-chain monoenes in the cardiac lipids was positively correlated to the dietary levels of these acids. The incidence of lesions found in heart, liver, and skeletal muscle was significantly higher in chickens fed RSO's high in 22:1 than in chickens fed control or soybean oil, and the incidence significantly correlated to the level of 22:1 in the diet. The incidence of heart and muscle lesions and sinusoidal distention in chickens fed RSO's low in 22:1 was not significantly different from that of chickens fed the control diet or soybean oil, but the incidence of hepatic necrosis was significantly higher for chickens fed RSO's low in 22:1 compared to those fed the control diet or soybean oil.

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Section: Discussionsupporting

confidence: 92%

Section: C Q Csupporting

confidence: 92%

Section: Discussionmentioning

confidence: 96%

Section: C Q Cmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Growth, Heart Weight, Cardiac Lipid, and Pathology of Chickens Fed Soybean Oil or Oil Extracted from Different Rapeseed Cultivars

Hulan¹,

Corner²,

Nash³

et al. 1982

Poultry Science

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Effects of High and Low Erucic Acid Rapeseed Oils on Energy Metabolism and Mitochondrial Function of the Chick

Renner

Innis

Clandinin

1979

The Journal of Nutrition

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Duplicate experiments were conducted to compare energy utilization, growth, cardiac mitochondrial oxidative phosphoryl,tion, and mitochondrial membrane fatty acid composition of chicks fed diets containing 20 parts of high erucic acid rapeseed oil (HER), low erucic acid rapeseed oil (LER) or sunflower seed oil (SFO) for 24 days. Chicks fed diets containing HER deposited less fat and utilized energy less efficiently (kcal gained/kcal consumed) than chicks fed diets containing either LER or SFO. Energetic efficiency and fat deposition of chicks pair-fed diets containing LER were significantly lower than for chicks fed diets containing SFO. Cardiac mitochondria isolated from chicks fed diets containing either HER or LER for 24 days had significantly reduced ADP/O ratios and reduced rates of ATP synthesis utilizing pyruvate and malate as the respiratory substrates when compared with mitochondria isolated from chicks fed SFO. Diet induced transitions in fatty acid composition of cardiac mitochondrial membranes were also observed. The composition of fat ingested affected the fatty acid composition of mitochondrial diphosphatidyl glycerol more than the fatty acid composition of phosphatidyl choline or phosphatidyl ethanolamine. The linoleic acid content of mitochondrial diphosphatidyl glycerol was lower and the gadoleic acid and erucic acid content higher for chicks fed diets containing rapeseed oils than for chicks fed SFO containing diets. These studies indicate that a complex dynamic mechanism exists associating dietary fat with mitochondrial structural-functional changes and energetic efficiency in the growing chick.

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Dietary Erucic Acid Induces Fat Accumulation, Hepatic Oxidative Damage, and Abnormal Lipid Metabolism in Nile Tilapia (Oreochromis niloticus)

Ma,

Li,

Xie

et al. 2024

Aquaculture Nutrition

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Erucic acid (EA) in rapeseed oil has adverse effects on terrestrial animal and fish health. However, its antinutritional role in fish remains unclear due to the limited information on EA. Therefore, this study was conducted to assess the impact of EA on growth performance, antioxidative capacity, fatty acid profile, and lipid metabolism in tilapia. Six diets containing different amounts of EA (0, 3, 6, 12, 20, and 27 g/kg diet) were fed to tilapia (initial weight: 3.01 ± 0.01 g) for 8 weeks. The results exhibited that dietary EA did not affect growth performance but remarkedly increased the crude lipid contents (in the whole body, liver, and muscle). It also markedly increased the levels of low‐density lipoprotein cholesterol, total cholesterol, nonesterified fatty acids, and triglyceride in the liver and serum in a dose‐dependent manner. The EA groups had lower values of total superoxide dismutase, total antioxidant capacity, catalase, and higher activities of aspartate aminotransferase and alanine aminotransferase, as dietary EA levels increased. Feeding fish with diets containing EA (20 and 27 g/kg diet) significantly increased the malondialdehyde content. Moreover, dietary EA greatly altered the fatty acid profile in the liver and muscle. It especially elevated the percentages of C18 : 2n‐6, C20 : 1n‐9, and C22 : 1n‐9 while decreasing the C18 : 0 and C16 : 0 levels. When the levels of EA in diets were 12, 20, and 27 g/kg, genes correlated with lipophagy, lipolysis, and β‐oxidation were significantly reduced. Meanwhile, genes concerned in triglyceride synthesis were largely increased in the liver and muscle. In summary, high‐dose EA (20 g/kg diet) in the diets significantly induced fat accumulation, hepatic oxidative damage, and abnormal lipid metabolism in tilapia. The current findings expand our understanding on the antinutritional role of EA in lipid homeostasis and fish health.

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Changes in Cardiac Lipids of Chicks Fed Rapeseed Oils With Different Levels of Erucic Acid

Cited by 5 publications

References 9 publications

Growth, Heart Weight, Cardiac Lipid, and Pathology of Chickens Fed Soybean Oil or Oil Extracted from Different Rapeseed Cultivars

Growth, Heart Weight, Cardiac Lipid, and Pathology of Chickens Fed Soybean Oil or Oil Extracted from Different Rapeseed Cultivars

Effects of High and Low Erucic Acid Rapeseed Oils on Energy Metabolism and Mitochondrial Function of the Chick

Dietary Erucic Acid Induces Fat Accumulation, Hepatic Oxidative Damage, and Abnormal Lipid Metabolism in Nile Tilapia (Oreochromis niloticus)

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