Changes in emotion-related EEG components and brain lateralization response to negative emotions in adolescents with nonsuicidal self-injury: An ERP study

Zhao, Lin; Zhou, Dongdong; Ma, Lei; Hu, Jinhui; Chen, Ran; He, Xiaoqing; Peng, Xinyu; Jiang, Zhenghao; Ran, Liuyi; Xiang, Jiaojiao; Zeng, Qinghui; Zhou, Yi; Dai, Linxi; Zhang, Qi; Su, Hong; Wang, Wo; Kuang, Li

doi:10.1016/j.bbr.2023.114324

Cited by 8 publications

(5 citation statements)

References 40 publications

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“…The ERP component during this time period is the P300 component, which reflects the brain’s cognitive executive processes in response to stimuli. Our previous study ( 39 ) found that MDD adolescents with NSSI showed an increase in P300 amplitude, but in the present study, we did not find significant changes in MS 1 and MS 2 parameters in the cross-sectional analysis. For this result, we tried to explain that although the main ERP component present during this time period is P300, there may be other ERPs, and therefore, MS 1 and MS 2 cannot be directly equated to P300 and need to be considered synergistically.…”

Section: Discussioncontrasting

confidence: 97%

“…The ERP component that appears during this time period is the N250 component, which reflects the early attention and monitoring process of the brain to the received stimulation. In our previous study ( 39 ), we found that MDD adolescents with NSSI exhibited an increase in N250 amplitude (absolute value), indicating the presence of impaired early attention and monitoring function in MDD adolescents with NSSI. In this study, we found an increase in MS 4 coverage and occurrence in MDD adolescents with NSSI compared to the other two groups, reconfirming this view from a microstate perspective.…”

Section: Discussionmentioning

confidence: 64%

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Changes in microstates of first-episode untreated nonsuicidal self-injury adolescents exposed to negative emotional stimuli and after receiving rTMS intervention

Zhao

Zhou

et al. 2023

Front. Psychiatry

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BackgroundNonsuicidal self-injury (NSSI) is a common mental health threat in adolescents, peaking in adolescence with a lifetime prevalence of ~17%–60%, making it a high-risk risk factor for suicide. In this study, we compared changes in microstate parameters in depressed adolescents with NSSI, depressed adolescents, and healthy adolescents during exposure to negative emotional stimuli, and further explored the improvement of clinical symptoms and the effect of microstate parameters of repetitive transcranial magnetic stimulation (rTMS) in depressed adolescents with NSSI, and more evidence was provided for potential mechanisms and treatment optimization for the occurrence of NSSI behaviors in adolescents.MethodsSixty-six patients with major depressive disorder (MDD) exhibiting NSSI behavior (MDD + NSSI group), 52 patients with MDD (MDD group), and 20 healthy subjects (HC group) were recruited to perform neutral and negative emotional stimulation task. The age range of all subjects was 12–17 years. All participants completed the Hamilton Depression Scale, the Patient Health Questionnaire-9, the Ottawa Self-Injury Scale and a self-administered questionnaire to collect demographic information. We provided two different treatments to 66 MDD adolescents with NSSI; 31 patients received medication and completed post-treatment scale assessments and EEG acquisitions, and 21 patients received medication combined with rTMS and completed post-treatment scale assessments and EEG acquisitions. Multichannel EEG was recorded continuously from 64 scalp electrodes using the Curry 8 system. EEG signal preprocessing and analysis was performed offline, using the EEGLAB toolbox in MATLAB. Use the Microstate Analysis Toolbox in EEGLAB for segmentation and computation of microstates, and calculate a topographic map of the microstate segmentation of the EEG signal for a single subject in each dataset, and four parameters were obtained for each microstate classification: global explained variance (GEV), mean duration (Duration), average number of occurrences per second (Occurrence), and average percentage of total analysis time occupied (Coverage), which were then statistically analyzed.ResultsOur results indicate that MDD adolescents with NSSI exhibit abnormalities in MS 3, MS 4, and MS 6 parameters when exposed to negative emotional stimuli compared to MDD adolescents and healthy adolescents. The results also showed that medication combined with rTMS treatment improved depressive symptoms and NSSI performance more significantly in MDD adolescents with NSSI compared to medication treatment, and affected MS 1, MS 2, and MS 4 parameters in MDD adolescents with NSSI, providing microstate evidence for the moderating effect of rTMS.ConclusionMDD adolescents with NSSI showed abnormal changes in several microstate parameters when receiving negative emotional stimuli, and compared to those not receiving rTMS treatment, MDD adolescents with NSSI treated with rTMS showed more significant improvements in depressive symptoms and NSSI performance, as well as improvements in EEG microstate abnormalities.

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Section: Discussioncontrasting

confidence: 97%

Section: Discussionmentioning

confidence: 64%

Changes in microstates of first-episode untreated nonsuicidal self-injury adolescents exposed to negative emotional stimuli and after receiving rTMS intervention

Zhao

Zhou

et al. 2023

Front. Psychiatry

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“…31 In the field of behavioral studies, emotions are a key determinant of human behavior. 42,52 On the base of cognitive appraisal theory of emotions and mood maintenance hypothesis, risk perception induced psychological insecurity should trigger a series of risky behaviors. More precisely, peoples' high psychological insecurity can stimulate their motivation to pursue psychological security, so they tend to choose to take risks to try to change the status quo, that is, reduce their own psychological insecurity and enhance their psychological security.…”

Section: Dovepressmentioning

confidence: 99%

“…non-suicidal self-injury). 52 Chen et al found that high emotional insecurity levels of junior middle school students are more likely to develop aggressive behavior. 41 Wu et al found that job insecurity can lead to emotional exhaustion, thereby causing employees to engage in unsafe behaviors.…”

Section: Dovepressmentioning

confidence: 99%

How Does Psychological Distance Influence Public Risky Behavior During Public Health Emergencies

Gao,

Sun

2024

RMHP

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Background Public health emergencies not only threaten the physical and mental health of the public but also trigger a series of risky behaviors of the public, which in turn lead to the emergence or intensification of risk events, disrupting existing economic and social order. Purpose Based on construal level theory, cognitive appraisal theory of emotions and mood maintenance hypothesis, the study aims to investigate the collectively effect of risk perception and psychological insecurity in the connection between psychological distance and public risky behavior. Participants and Methods Cross-sectional data was derived from 257 China urban residents. All participants finished the psychological distance scale, risk perception scale, psychological insecurity scale, and risky behavior scale. The research hypothesis was tested using the PROCESS macro. Results The direct impact of psychological distance on risky behavior was not significant (β=−0.018, p>0.05). The indirect impact of psychological distance on risky behavior was significant. In other words, the impact of psychological distance on risky behavior was serially mediated via risk perception and psychological insecurity (β=0.011, 95% CI= [0.0013, 0.025]). Conclusion Risk perception and psychological insecurity play serial mediating roles in the relationship between psychological distance and public risky behavior. We conclude that during public health emergencies, public health managers should pay extra attention to the risk perception and psychological insecurity level of the public with closer psychological distance, take measures to reduce their risk perception, enhance their psychological security, and reduce their risky behavior, thereby ensuring the physical and mental health of the public and maintaining the stability of economic and social order.

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“…Consequently, the TCO paradigm is thought to have a higher ecological validity in the evaluation of inhibitory control than others (e.g., standard GNG and SS tasks) ( 21 , 23 – 25 ). TCO paradigms have been widely used in various applications, such as addiction ( 24 ), depression ( 25 ), restrained eaters ( 26 ), acute stress ( 27 ), visually induced motion sickness ( 28 ), avoidant attachment-style individuals ( 29 ), nonsuicidal self-injury ( 30 ), and male smokers ( 20 ). However, it has not fully investigated the issue of how to apply TCO paradigms to understand inhibitory control deficits in the comorbidity of ADHD and SLD.…”

Section: Introductionmentioning

confidence: 99%

Reduced inhibition control ability in children with ADHD due to coexisting learning disorders: an fNIRS study

Liu,

Chi,

2024

Front. Psychiatry

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IntroductionInhibition control, as the core component of executive function, might play a crucial role in the understanding of attention deficit/hyperactivity disorder (ADHD) and specific learning disorders (SLD). Inhibition control deficits have been observed in children with ADHD or SLD. This study sought to test in a multi-modal fashion (i.e., behavior and plus brain imaging) whether inhibition control abilities would be further deteriorated in the ADHD children due to the comorbidity of SLD.MethodA total number of 90 children (aged 6-12 years) were recruited, including 30 ADHD, 30 ADHD+SLD (children with the comorbidity of ADHD and SLD), and 30 typically developing (TD) children. For each participant, a 44-channel functional near infrared spectroscopy (fNIRS) equipment was first adopted to capture behavioral and cortical hemodynamic responses during a two-choice Oddball task (a relatively new inhibition control paradigm). Then, 50 metrics were extracted, including 6 behavioral metrics (i.e., OddballACC, baselineACC, totalACC, OddballRT, baselineRT, and totalRT) and 44 beta values in 44 channels based on general linear model. Finally, differences in those 50 metrics among the TD, ADHD, and ADHD+SLD children were analyzed.ResultsFindings showed that: (1) OddballACC (i.e., the response accuracy in deviant stimuli) is the most sensitive metric in identifying the differences between the ADHD and ADHD+SLD children; and (2) The ADHD+SLD children exhibited decreased behavioral response accuracy and brain activation level in some channels (e.g., channel CH35) than both the ADHD and TD children.DiscussionFindings seem to support that inhibition control abilities would be further decreased in the ADHD children due to the comorbidity of SLD.

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Changes in emotion-related EEG components and brain lateralization response to negative emotions in adolescents with nonsuicidal self-injury: An ERP study

Cited by 8 publications

References 40 publications

Changes in microstates of first-episode untreated nonsuicidal self-injury adolescents exposed to negative emotional stimuli and after receiving rTMS intervention

Changes in microstates of first-episode untreated nonsuicidal self-injury adolescents exposed to negative emotional stimuli and after receiving rTMS intervention

How Does Psychological Distance Influence Public Risky Behavior During Public Health Emergencies

Reduced inhibition control ability in children with ADHD due to coexisting learning disorders: an fNIRS study

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