Changes in health‐related quality of life after discharge from an intensive care unit: a systematic review

Gerth, Alice M. J.; Hatch, Robert Alan; Young, John; Watkinson, Peter

doi:10.1111/anae.14444

Cited by 102 publications

(124 citation statements)

References 74 publications

(223 reference statements)

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“…Also, HRQoL at admission was associated with both LOS and readmission. Several previous studies have reported that HRQoL returns to population norms one year or longer after discharge from intensive care units [20]. In our study, we found that HRQoL showed partial improvements even as early as at discharge.…”

Section: Discussionsupporting

confidence: 62%

“…For elderly patients hospitalized for acute illness, HRQoL is known to be an important determinant of hospital outcomes (e.g., LOS) [9,[20][21][22][23], although in dispute, other studies reported no relationship [24]. Higher baseline HRQoL is considered to have better functional reserves or ability to recover and could thus predict shorter hospital stays [10].…”

Section: Discussionmentioning

confidence: 99%

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Health-Related Quality of Life Measured by EQ-5D in Relation to Hospital Stay and Readmission in Elderly Patients Hospitalized for Acute Illness

Lin

Huang

et al. 2020

IJERPH

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We evaluated the predictability of self-reported Health-related quality of life (HRQoL) assessed by the 3-level 5-dimensional Euro-Quality of Life tool (EQ-5D-3L) and the EQ-Visual Analog Scale (EQ-VAS) on clinical outcomes of elderly patients who were admitted to an acute geriatric ward. A total of 102 participants (56.9% men) with a median age of 81.0 years (interquartile range or IQR: 76.0–85.3 years) were studied. The age-adjusted Charlson comorbidity index was 5.0 (IQR: 4.0–6.0) with a median length of stay (LOS) of 9.0 days (IQR: 7.0–15.0 days). No death occurred during hospitalization, and within 30 days after discharge, 15 patients were readmitted. During hospitalization, the EQ-5D-3L index was 0.440 at admission and that improved to 0.648 at discharge (p < 0.001). EQ-VAS scores also improved similarly from 60 to 70 (p < 0.001). Physical, cognitive function, frailty parameters (hand grip strength and walking speed), and nutritional status at admission all improved significantly during hospitalization and were related to EQ-5D-3L index or EQ-VAS scores at discharge. After controlling for relevant factors, EQ-5D-3L index at admission was found to be associated with LOS. In addition, EQ-VAS was marginally related to readmission. HRQoL assessment during hospitalization could be useful to guide clinical practice and to improve outcome.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Health-Related Quality of Life Measured by EQ-5D in Relation to Hospital Stay and Readmission in Elderly Patients Hospitalized for Acute Illness

Lin

Huang

et al. 2020

IJERPH

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“…However, Orwelius and colleagues 30 showed that the effect of ICU admission on the proportion of patients reporting pain (44.3% of the post-ICU population vs 25.7% of those that were not admitted to the ICU) was mitigated once the number of pre-existing co-morbidities was accounted for in the reference population. A systematic review of HRQoL after ICU discharge, including 48 studies, 18 identified a significant decrement in pain domains compared with population norms when using the EQ-5D at 12 months (20 studies). However, when the SF-36 was used (30 studies), this decrement was not significant, and it is unclear whether the different results can be accounted for by the choice of outcome measure or other study-specific characteristics.…”

Section: Prevalencementioning

confidence: 99%

Chronic pain in critical care survivors: a narrative review

Kemp

Laycock

Costello

et al. 2019

British Journal of Anaesthesia

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Chronic pain is an important problem after critical care admission. Estimates of the prevalence of chronic pain in the year after discharge range from 14% to 77% depending on the type of cohort, the tool used to measure pain, and the time point when pain was assessed. The majority of data available come from studies using health-related quality of life tools, although some have included pain-specific tools. Nociceptive, neuropathic, and nociplastic pain can occur in critical care survivors, but limited information about the aetiology, body site, and temporal trajectory of pain is currently available. Older age, pre-existing pain, and medical co-morbidity have been associated with pain after critical care admission. No trials were identified of interventions to target chronic pain in survivors specifically. Larger studies, using pain-specific tools, over an extended follow-up period are required to confirm the prevalence, identify risk factors, explore any association between acute and chronic pain in this setting, determine the underlying pathological mechanisms, and inform the development of future analgesic interventions.

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“…Interventions to help recover from critical illness are likely to affect areas such as physical function and social ability, especially during the rst year after hospital discharge. [31].…”

Section: Life After Critical Illnessmentioning

confidence: 99%

The Physical and Mental Impact of Surviving Sepsis – A Qualitative Open Interview Study

Apitzsch¹,

Larsson²,

Larsson³

et al. 2020

Preprint

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Background: This study aims to illuminate how sepsis survivors experience sepsis and the impact of sepsis as well as the quality of life thereafter. Methods: A qualitative open interview study with eight sepsis survivors was performed. A content analysis inspired by Burnard was made. Results: Four main categories emerged during the analysis; The experience of health care and being a sepsis patient, New circumstances´ impact on life, Family and social interactions, and The psychological impact on life. The lack of information on how sepsis can impact the survivors’ lives and what to expect can lead to prolonged agony. The long recovery time comes as an unexpected and unpleasant surprise to those affected. Initially, the sepsis survivors are almost euphoric that they have survived, which can later lead to chock and trauma when they realize that they could have died. This insight needs to be processed in order to reach reconciliation with how life will turn out after sepsis. Conclusion: Sepsis has a huge impact on both physical and mental aspects of life. Many survivors suffer from persistent residual symptoms of varying degrees to which they have to adapt. The sepsis survivors need individually adjusted information about the sepsis recovery trajectory and what to expect during and after the hospital stay.

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Changes in health‐related quality of life after discharge from an intensive care unit: a systematic review

Cited by 102 publications

References 74 publications

Health-Related Quality of Life Measured by EQ-5D in Relation to Hospital Stay and Readmission in Elderly Patients Hospitalized for Acute Illness

Health-Related Quality of Life Measured by EQ-5D in Relation to Hospital Stay and Readmission in Elderly Patients Hospitalized for Acute Illness

Chronic pain in critical care survivors: a narrative review

The Physical and Mental Impact of Surviving Sepsis – A Qualitative Open Interview Study

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