Changes in muscle fiber size and in the composition of myosin heavy chain isoforms of rabbit extraocular rectus muscle following recession surgery

Abstract

Transient atrophy and regeneration were observed only in the GL, and the changes in the MyHCIIb plus MyHCeom appeared to be related to these changes.

Inflammatory response during slow- and fast-twitch muscle regeneration

“…In addition to the histological analyses, the progress of regeneration could be assessed by analysis of the expression of protein characteristic for newly formed muscles, i.e., embryonic myosin heavy chain isoform (eMyHC) . In intact muscles eMyHC is not detectable (Fig.…”

“…In the current study, we focused on a developmental marker of myogenesis, i.e., embryonic MyHC, which during muscle regeneration is expressed exclusively in newly formed multinucleated myotubes. The dynamics of its expression may differ, however, depending on the method of muscle injury . Nevertheless, it marks newly formed muscle fibers.…”

“…The dynamics of its expression may differ, however, depending on the method of muscle injury. 11,12,29,36,37,48 Nevertheless, it marks newly formed muscle fibers.…”

Increased vertical dimension effects on masseter muscle fiber phenotype during maturation

“…16 In cranial nerve innervated extraocular muscle, a surgical shortening of the muscle caused a significant decrease in MyHC IIb protein 3 days after surgery. 17 One advantage of this study was the examination of regions of the masseter muscle to assess potential local plastic changes after a VDO increase. It has been shown previously in the rabbit masseter that this muscle has multiple functional compartments that are activated at different times in the chewing cycle, depending on the task.…”