2014
DOI: 10.1016/j.drugalcdep.2013.10.011
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Changes in quality of life (WHOQOL-BREF) and addiction severity index (ASI) among participants in opioid substitution treatment (OST) in low and middle income countries: An international systematic review

Abstract: Background Opioid substitution treatment (OST) can increase quality of life (WHOQOL-BREF) and reduce addiction severity index (ASI) scores among participants over time. OST program participants have noted that improvement in quality of life is one of the most important variables to their reduction in drug use. However, there is little systematic understanding of WHOQOL-BREF and ASI domain changes among OST participants in low and middle-income countries (LMIC). Methods Utilizing PRISMA guidelines we conducte… Show more

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Cited by 91 publications
(69 citation statements)
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“…In addition, significant changes were observed in all subscales of WHOQOL -BREF, including physical health, psychological health, social relationship, and environmental health. These significant changes in both quality of life and addiction severity were similar to the results described in a multisite clinical trial, which assessed Opioid Substitution Treatment (OST) in 13 treatment programs in seven low and middle income countries (24). The quality of life and addiction severity scales are important findings that are associated with improved retention (25).…”
Section: Discussionsupporting
confidence: 66%
“…In addition, significant changes were observed in all subscales of WHOQOL -BREF, including physical health, psychological health, social relationship, and environmental health. These significant changes in both quality of life and addiction severity were similar to the results described in a multisite clinical trial, which assessed Opioid Substitution Treatment (OST) in 13 treatment programs in seven low and middle income countries (24). The quality of life and addiction severity scales are important findings that are associated with improved retention (25).…”
Section: Discussionsupporting
confidence: 66%
“…Medication assisted therapy, such as buprenorphine/ naloxone, reduces rates of overdose and overdose death [41][42][43], reduces recidivism in emergency departments and within the criminal justice system [44,45], increases compliance and adherence to other medical services [31,32]. But most importantly, it helps put people on the path to recovery and enhances their quality of life [46,47].…”
Section: Resultsmentioning
confidence: 99%
“…The WHOQOL-BREF has proven to be an instrument that is sensitive to the changes caused by treatment, with methadone (Feelemyer, Des Jarlais, Arasteh, Phillips, & Hagan, 2014) and without (Sánchez-Hervás, Tomás-Gradolí, Molina Bou, del Olmo Gurrea, & Morales Gallús, 2002). In general, the findings show that people improve their quality of life when they stop using non-prescribed opiates and undergo treatment with methadone (Padaiga, Subata, & Vanagas, 2007).…”
Section: Introductionmentioning
confidence: 63%