Changes In Serum Electrolyte Levels In Typhoid Fever Patients Attending Minna General Hospital

Кабіру, А.; Tahir, Ismail; Garba, M; Fa, Kuta; Jibril, A; Shuaib, MA

doi:10.4314/njtr.v11i1.10

Cited by 1 publication

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“…Some signs and symptoms of typhoid such as fever, diarrhoea and vomiting can lead to dehydration and sodium deficiency. This is confirmed by the stance of Kabiru et al [14].…”

Section: Sodium (Nasupporting

confidence: 71%

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Evaluation of Some Hepato- Renal Biochemical Parameters in Typhoid Fever Patients in Yenagoa, Bayelsa State Nigeria

Wankasi

George

Alabrah

et al. 2022

IJTDH

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Introduction: Typhoid fever infection is one of the most prevalent diseases in developing countries. It is caused by Salmonella species and can affect multiple organs in the body if left untreated. The purpose of this study was to determine the biochemical patterns of renal and liver biochemical parameters in patients admitted with typhoid fever. Methodology: A total of 100 subjects were recruited for the study, with 50 typhoid-positive patients and 50 typhoid-negative individuals serving as controls. Blood samples collected from the subjects were analyzed for Salmonella Typhi titre, sodium (Na), potassium (K), chloride (Cl), urea, creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) using WHO-approved methods. The data obtained were statistically evaluated in SPSS version 22. Results: The comparison between the positive and negative titres of Salmonella Typhi showed a significant increase in concentrations of creatinine and AST in the positive titres, whereas sodium decreased. Conclusion: This result suggests that patients with high titers of Salmonella Typhi are more susceptible to hepatocellular injury, muscle wasting, and hyponatremia. Therefore, liver and kidney function tests should be essential clinical tests for the management of typhoid fever.

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“…Some signs and symptoms of typhoid such as fever, diarrhoea and vomiting can lead to dehydration and sodium deficiency. This is confirmed by the stance of Kabiru et al [14].…”

Section: Sodium (Nasupporting

confidence: 71%

“…Reports have shown the effects of typhoid fever on renal function. These appear and are detected by various disorders of renal biochemical parameters such as electrolytes, urea and creatinine [11,14,15]. Biochemical changes in liver enzymes that indicate liver damage have been reported in patients infected with typhoid fever [9,16,17].…”

Section: Introductionmentioning

confidence: 99%