Changes in the Extracellular Compartment of Muscle and Skin During Normal and Retarded Development

Em, Widdowson

doi:10.1159/000385152

Cited by 3 publications

(1 citation statement)

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“…3a), although immunolabeling reveals that both types I and III collagen are present throughout the putative dermis and subdermis, and concentrated in a narrow zone underlying the dermal-epidermal junction (10). The dermal mesenchyma is enriched with hyaluronic acid that retains a high water content (24) and is poor in sulfated GAGs (Eigs. 4a and 4d).…”

Section: Cellular Dermismentioning

confidence: 99%

Embryogenesis of the Dermis in Human Skin

Smith

Holbrook

1986

Pediatric Dermatology

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The process of human dermal development has been examined from the stage of the embryonic mesenchymal dermis (5-8 weeks of gestation) through the formation of the fibrous dermal connective (end of the first trimester), and during the growth of the fetal dermis (second and third trimesters) until birth. The elaboration of dermal organization and the overall increase in dermal thickness, largely consequences of extracellular, fibrous matrix accumulation, parallel the development and growth of the fetus as a whole. Although the mechanisms that determine the formation of the connective tissue architecture are not fully understood, the structural, histochemical, and biochemical changes that occur throughout development suggest processes that may be important in human dermal embryogenesis.

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Section: Cellular Dermismentioning

confidence: 99%