Changes in the Mineral Coinposition of Enamel and Dentin of the Incisors in Vitamin E‐Deficient Rnts¹

The actions of α-tocopherol and protein upon the incisor tooth of the rat, and the influence of vitamin A upon α-tocopherol activity

“…Both these granules and also the pigment stain intensely for iron by the ferrocyanide-HC1 technique. It is well known that the tooth pigment is rich in iron (Dam, Granados & Maltesen, 1950), but in what form is still undecided. I n vitamin E deficiency the iron content of these ameloblasts is greatly reduced and they may contain none at all.…”

“…It has been suggested (Dam et al 1950) that a-tocopherol plays an important part in the iron metabolism of the tooth, as witnessed by its protective effect on the pigment. Though this is undoubtedly so, it would appear that this role is not specific to this vitamin.…”

Mineral Metabolism (Animal)

“…of man ganese are adequate for growth, levels of above 20 p.p.m. Dam and his co-workers (195) show that in deficient rats the manganese of enamel and dentine is considerably higher, 0.093 as compared with 0.034 per cent in the enamel and 0.105 as compared with 0.025 per cent than in the dentine of normal rats. Since levels of 60 to 70 p.p.m.…”

The Fat–soluble Vitamins in Metabolic Processes

“…Moore (1942) found that deficiency of vitamin E in the same animal causes a loss of the brown colour of the incisor teeth, as previously reported in deficiency of vitamin A. Deprivation of vitamin E bleaches the teeth much more readily in albino rats than in piebalds. Dam, Granados & Maltesen (1950) have drawn attention to the high iron content of the brown pigment. They report that in teeth that have been depigmented by deficiency of vitamin E the decrease in iron is accompanied by a rise in manganese.…”