Changes of some lipid and lipid peroxidation characteristics in obese people as a result of a low energy diet

Dworschák, E.; Lugasi, A.; Pados, George; Bíró, G.; Zsinka, A.

doi:10.1007/bf02019508

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…Other variables showed no significant difference. a restricted energy diet of for three months, SOD activity was reduced, whereas the GPX did not change (28). In the present study mean of SOD activity decreased somewhat (but not significantly) after intervention.…”

Section: Discussioncontrasting

confidence: 48%

The effect of weight reduction on antioxidant enzymes and their association with dietary intake of vitamins A, C and E

Ramezanipour

Jalali

Sadrzade-Yeganeh

et al. 2014

Arq Bras Endocrinol Metab

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Objective: Our goal was to assess the effects of weight loss on antioxidant enzymes of red blood cells and it's relation with vitamins A, E and C intake in 30 obese women. Subjects and methods: General information, anthropometric measurements, 3-day food recall, and fasting blood samples were collected from 30 obese women at the beginning of the study and after 3 months intervention. Weight loss was set at about 10% of their weight before the intervention. Results: Glutathione reductase and catalase activities showed a significant increase (P < 0.01) after weight reduction, but no significant changes were seen in the superoxide dismutase and glutathione peroxidase activities. There was a positive linear correlation between daily vitamin C intake with superoxide dismutase enzyme after intervention (P = 0.004, r = 0.507). There was a negative linear correlation between vitamin E intake and glutathione peroxidase activity before intervention (P = 0.005, r = -0.5). A negative correlation was found between daily vitamin A intake and glutathione reductase enzyme before and after intervention (r = -0.385, r = -0.397, P < 0.05) respectively. No significant correlation was observed between vitamins A, C, E amounts and catalase activity. Conclusions: Ten percent weight reduction can have a significant role in increasing antioxidant enzymes activities, especially glutathione reductase, and catalase enzymes in obese women. However, it is important to take into consideration a balanced amount of certain nutrients while administering a diet with limited energy. Arq Bras Endocrinol Metab. 2014;58(7):744-9 Keywords Obesity; enzymic antioxidants; weight reduction RESUMO Objetivo: Nosso objetivo foi avaliar os efeitos da perda de peso sobre as enzimas antioxidantes de eritrócitos, e a relação destas com a ingestão das vitaminas A, E e C. Sujeitos e métodos: Foram coletadas informações gerais e medidas antropométricas, registro alimentar de três dias e amostras de sangue em jejum de 30 mulheres obesas no início do estudo e depois de três meses da intervenção. A perda de peso determinada antes da intervenção foi de 10% do peso. Resultados: As atividades da glutationa redutase e da catalase mostraram aumento significativo (P < 0,01) depois da perda de peso, mas não houve mudanças significativas nas atividades da superóxido dismutase e da glutationa peroxidase. Foi observada uma correlação linear positiva entre a ingestão diária de vitamina C e a enzima superóxido dismutase após a intervenção (P = 0,004, r = 0,507). Houve uma correlação linear negativa entre a ingestão de vitamina E e a atividade da glutationa peroxidase antes da intervenção (P = 0,005, r = -0,5). Foi observada uma correlação negativa entre a ingestão diária de vitamina A e a enzima glutationa redutase antes e depois da intervenção (r = -0,385, r = -0,397, P < 0,05), respectivamente. Não foram observadas correlações significativas entre as vitaminas A, C, E e os níveis e a atividade da catalase. Conclusões: Uma redução de 10% no peso pode ter um papel signifi...

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Section: Discussioncontrasting

confidence: 48%

The effect of weight reduction on antioxidant enzymes and their association with dietary intake of vitamins A, C and E

Ramezanipour

Jalali

Sadrzade-Yeganeh

et al. 2014

Arq Bras Endocrinol Metab

View full text Add to dashboard Cite

show abstract

“…After weight loss SOD was reduced and GPX was unchanged. 22 This study confirms our present results, the average SOD was reduced after the intervention and average GPX was slightly increased with no meaningful connection.…”

Section: Discussionsupporting

confidence: 90%

“…Dworschak et al, 22 measured the enzymatic antioxidants GPX and SOD. Fifty four obese people (13 Male, 41 female) were assigned to a low calorie diet 5-6mj/day for threemonths.…”

Section: Discussionmentioning

confidence: 99%

Effects of Weight Loss on Enzymatic Antioxidants and its Correlation amongst Overweight Women

Ramezanipour¹

2017

AOWMC

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The present study is a clinical trial carried out to evaluate the effects of weight loss on enzymatic antioxidants and their correlations. Methods: Thirty obese women, between the ages of 19-50, were included in this study. A low calorie diet with a 500-1000calorie deficit was recommended with the aim of 10% weight loss. To measure nutrient intake, general questionnaires and 24hour recall forms were used three days prior and after intervention. A 10ml blood sample was taken from each subject before and after intervention for the measurement of enzymatic antioxidants in the red blood cells. Results: Weight loss caused a significant increase (p<0.01) in the mean glutathione reductase (GR) and catalase (CAT). No statistically significant change occurred in the mean values of superoxide dismutase (SOD) or glutathione peroxidase (GPX). Based on the Pearson's correlation coefficient between the dependent variables (GPX, CAT, GR, SOD) of the participants after intervention, there was a meaningful correlation between the dependent variables SOD with GPX at P<0.001 and r=0.618 and between SOD with CAT at P<0.05 and r=0.424. Also between GPX with CAT at P=0.003 and r=0.527 and between CAT with GR at P<0.05 and r=0.366 there is a meaningful correlation after intervention. Conclusion: A 10% reduction in body weight can have a significant effect on increasing the levels of enzymatic antioxidants in obese women. There is the possibility of greater increase in enzymatic antioxidants and their correlation with weight loss and the reduction of BMI to a normal range in obese people.

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Changes of some lipid and lipid peroxidation characteristics in obese people as a result of a low energy diet

Cited by 2 publications

References 8 publications

The effect of weight reduction on antioxidant enzymes and their association with dietary intake of vitamins A, C and E

The effect of weight reduction on antioxidant enzymes and their association with dietary intake of vitamins A, C and E

Effects of Weight Loss on Enzymatic Antioxidants and its Correlation amongst Overweight Women

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