Changing trends in antimicrobial resistance of major bacterial pathogens, 1985–2005: A study from a medical center in northern Taiwan

Abstract

Resistance to antimicrobial agents increased rapidly in the past two decades in Taiwan and has become very common in major bacterial pathogens. Continuous enforcement of policies to limit use of antimicrobial agents and active surveillance of antimicrobial resistance through a nationwide system are both warranted.

Severe infections in children with acute leukemia undergoing intensive chemotherapy can successfully be prevented by ciprofloxacin, voriconazole, or micafungin prophylaxis

“…Changes in the ciprofloxacin resistance of bacteria must be monitored during the prophylaxis period. According to a previous study, there was a significant increase in the rate of ciprofloxacin‐resistant gram‐negative organisms . The rate of ciprofloxacin‐resistant E. coli , Klebsiella pneumoniae , Pseudomonas aeruginosa , and Serratia marcescens significantly decreased during the prophylaxis period, whereas there was no change noted for Acinetobacter baumannii , Enterobacter cloacae , Proteus mirabilis , and Salmonella species.…”

Genetic Analysis of Glycopeptide-Resistant Staphylococcus epidermidis Strains from Bone and Joint Infections

“…S. epidermidis can develop antibiotic resistance and also form biofilm on implanted medical devices (3,4). In most countries, 75 to 90% of all hospital S. epidermidis isolates are resistant to methicillin (1,5). Resistance to fluoroquinolones, erythromycin, clindamycin, gentamicin, rifampin, tetracycline, and chloramphenicol is also frequent (1,(6)(7)(8).…”

Trends in Susceptibility of Vancomycin-Resistant Enterococcus faecium to Tigecycline, Daptomycin, and Linezolid and Molecular Epidemiology of the Isolates: Results from the Tigecycline In Vitro Surveillance in Taiwan (TIST) Study, 2006 to 2010

“…Although the incidence of infection due to VRE has risen in recent years in many countries (1,15), the incidence of VRE in Taiwan remains relatively low (3 to 7%) (15), especially compared to the incidence of hospital-acquired VRE infection in the United States (28%).VRE species are recovered from colonized rather than infected patients in many institutions (24), but VRE infection is associated with higher recurrence and mortality (21). In addition, the treatment regimens for VRE infections are limited to tigecycline, daptomycin, and linezolid.…”