Changing trends in seroprevalence rates of transfusion-transmitted diseases among blood donors in Jordan

Souan, Lina; Siag, Mahmoud; Al-Salahat, Hala; Al-Atrash, Tareq; Sughayer, Maher A.

doi:10.1186/s12879-021-06196-3

Cited by 5 publications

(7 citation statements)

References 21 publications

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“…The overall prevalence of anti-HBc in this study was 4.6%. Similar rates have been reported in Iran 4.9% 22 and Jordan (2.0-4.1%) 23 . Higher rates of anti-HBc positivity have been reported in studies conducted in Syria (10.3%) 24 .…”

Section: Discussionsupporting

confidence: 88%

Immunological Status of Hepatitis B Virus Infection Among Freshmen University Students in Yemen

Makdad

Al-Haifi²,

Al-Mutaa³

et al. 2023

Univ J Pharm Res

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Background: Hepatitis B virus (HBV) is a most important health problem, it's a global pandemic. Previous surveys showed a high prevalence of hepatitis B infection in Yemen. Hepatitis B vaccination is the most efficient way to prevent hepatitis B virus infection and its outcomes (such as hepatocellular carcinoma, cirrhosis, and liver failure). Aim: To measure the immune status of hepatitis B virus amongst first-year students at the faculties of Thamar University during the academic year 2021-2022. Methods: A total 196 of first-year students participated in this cross-sectional study and tested for anti-HBsAg and the antibody to HBV core antigen (anti-HBc) and HBsAg by using ELISA during the period from January to May 2022 at Thamar University. An anti-HBs antibody titer ≥10 mIU/mL was regarded as being protective against HBV infection. Results: In this study, 22.4% of the students had protective levels against hepatitis B, while 77.6% had a non-protective level. HBV markers showed that 19.90%, 2.55%, and 75.51% of the students had been vaccinated and immunized due to a previous infection and exposed to HBV infection respectively and only 2.04% of them were non-obvious cases. The prevalence of anti-HBc was 4.6%. Risk factors that showed statistical significance were found between positive anti-HBc and family history of HBV (p=0.01). Conclusion: The low prevalence of hepatitis B protection levels in Thamar University medical students needs further research and necessitates implementation of a screening and vaccination program for all non-immunized healthcare students. Peer Review History: Received: 24 December 2022; Revised: 13 February 2023; Accepted: 8 March 2023, Available online: 15 March 2023 Academic Editor: Dr. Iman Muhammad Higazy, National Research Center, Egypt, imane.higazy@hotmail.com Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewers: Rola Jadallah, Arab American University, Palestine, rola@aauj.edu Dr. Wadhah Hassan Ali Edrees, Hajja University, Yemen, edress2020@gmail.com Similar Articles: PREVALENCE OF HEPATITIS A VIRUS, HEPATITIS B VIRUS, AND HEPATITIS C VIRUS, AMONG PATIENTS WITH HEPATIC JAUNDICE IN SANA’A CITY, YEMEN: A HOSPITAL BASED STUDY PREVALENCE OF DIFFERENT HEPATITIS B VIRUS GENOTYPES AND RISK FACTORS ASSOCIATED AMONG SELECTED YEMENI PATIENTS WITH CHRONIC HEPATITIS B INFECTION

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Section: Discussionsupporting

confidence: 88%

Immunological Status of Hepatitis B Virus Infection Among Freshmen University Students in Yemen

Makdad

Al-Haifi²,

Al-Mutaa³

et al. 2023

Univ J Pharm Res

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“… 19 However, the seropositivity rate of the present study was higher than our previous study (1.9%). 16 A low prevalence of HBsAg was reported in Iraq (0.24%), 20 Jordan (0.3%), 21 and Malaysia (0.03%). 22 The present study revealed a lower prevalence rate of HBsAg than those reported rates in Saudi Arabia (3.24%), 23 Yemen (4.1%), 14 Sudan (5.8%), 24 Nigeria (5.8%), 25 Ethiopia (3.0%), 26 Cameroon (11.2%), 27 the Central African Republic (16.7%) 28 and Mauritania (11.8%).…”

Section: Discussionmentioning

confidence: 98%

“…33 Lower rates, however, were reported in studies in Iran 34 (4.9%), Saudi Arabia (5.7%), 35 and Jordan (2.0–4.1%). 21 …”

Section: Discussionmentioning

confidence: 99%

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Alzubiery¹,

Alharazi²,

Alcantara³

et al. 2022

IDR

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Purpose Hepatitis B virus (HBV) is one of the most common infectious pathogens worldwide. Various studies found a prevalence of HBV infection among blood donors ranging from 2% to 18%. Hence, this study aimed to provide an updated prevalence of HBsAg and anti-HBcAb among blood donors. Patients and Methods This was a cross-sectional study to investigate the donation records of blood donors in Sana’a, Yemen, over one year (January to December 2019). Eligible blood donors were included in the study. The serum samples of blood donors were tested for HBsAg and anti-HBcAb (IgG & IgM) using the electrochemiluminescence (ECL) and enzyme immunoassay (EIA) techniques. Results A total of 16,367 blood donors were recruited in this study, of whom 14,300 (87.4%) donated only once during this study (single, non-duplicated blood donors), while 2067 (12.6%) were repeated or duplicated. The overall prevalence of HBsAg and anti-HBcAb was 2.4% and 10.8%, respectively. Among single non-duplicated blood donors, HBsAg and Anti-HBcAb were 2.3% and 10.6% and 3.0% and 12.5% for repeated blood donors, respectively. There were statistically significant differences between HBsAg and Anti-HBcAb in terms of donor type and testing techniques. Conclusion The seroprevalence of HBsAg and anti-HBcAb among the blood donors was 2.0% and 10.3%, respectively. The ECL technique is more sensitive, has a lower error rate, and shows an advantage over the manual EIA technique. Duplicated blood donors influence the accuracy of the seroprevalence of HBsAg and anti-HBcAb.

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“…In the WHO's Eastern Mediterranean Region, it is estimated that 60 million people are infected with HBV [2]. Several hepatitis prevalence studies were conducted in Middle Eastern countries including Jordan [3][4][5]. In Jordan estimated population of the Kingdom by Administrative Divisions at end-year of 2021 was reported to be eleven million fifty-seven thousand [6].…”

Section: Introductionmentioning

confidence: 99%

“…In 2015 the Jordanian National Blood Bank recorded a 2% of the unceasing screening for HBV infection among blood donors [9]. However, recent studies reported unexplained increment in the prevalence rates of HBV and hepatitis C virus (HCV) infections among blood donors in 2019 and among pregnant females in Jordan (5%) [5,10]. To add on, a recent cluster of new cases of acute hepatitis of unknown origin among young children in multi-countries were reported by the WHO [11].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of hepatitis B knowledge, practices, and beliefs among the Jordanian population: A cross-sectional study

et al. 2022

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This study aimed to assess the knowledge, practices, and beliefs among the Jordanian population regarding hepatitis B virus (HBV) infection. A cross-sectional questionnaire was designed and used to recruit participants from October 5th through December 12th. Statistical analysis was conducted using SPSS. Descriptive statistical analysis was used to analyse the sociodemographic data, the Shapiro-Wilk test was used to assess the normality, Cronbach’s α was used to evaluate the reliability of the questionnaire and Point-biserial correlation was used to figure out whether there is an association between Score of knowledge and the dichotomous variables. A random sample of 432 participated in the study. The majority were females (n = 310, 71.8%), the mean age was 21 (42.0%) years,416 (96.3%) were urban inhabitants and most of them (n = 351, 81.3%) had bachelor’s degree. School/university (n = 280, 64.8%) were reported as a major source of information followed by TV/internet/social media 276 (63.9%). The total mean (± SD) of knowledge score regarding HBV infection symptoms, transmission modes and treatment was found 12.28 ± 3.2. Participants’ knowledge regarding symptoms including nausea, vomiting and loss of appetite was 73 (16.9%). More than 80% had good knowledge regarding the complications of HBV infection. Only 100 participant reported vaccination (23.1%) against the virus. Poor knowledge and low vaccination rate against HBV were found thus implementing comprehensive educational program for people highlighting the importance of vaccination against the virus is crucial.

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Changing trends in seroprevalence rates of transfusion-transmitted diseases among blood donors in Jordan

Cited by 5 publications

References 21 publications

Immunological Status of Hepatitis B Virus Infection Among Freshmen University Students in Yemen

Immunological Status of Hepatitis B Virus Infection Among Freshmen University Students in Yemen

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Evaluation of hepatitis B knowledge, practices, and beliefs among the Jordanian population: A cross-sectional study

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