Chapter 11D Analysis of chemicals related to the chemical weapons convention

Gas Chromatography Electron Ionization Mass Spectrometric Analysis of Trimethylsilyl Derivatives of Bis(2-Hydroxyethylthio)Alkanes and Bis(2-Hydroxyethylsulfonyl)Alkanes

“…Nevertheless, based on their modes of formation, they are depicted as two species, because, in the rest of the compounds, ions [7] and [8] were clearly distinguishable. Ions [10]- [14] could originate from various typical rearrangements and hydrogen exchange reactions. Some fragment ions in the lower part of the spectra were also of diagnostic value.…”

“…8 Verifi cation of CWC involves analysis (unequivocal identifi cation) of CWAs and their degradation products in samples collected by inspectors appointed by the Organization for Prohibition of Chemical Weapons (OPCW) from suspected CW production facilities. 9,10 Analysis is performed by the designated laboratories appointed by the OPCW. 11,12 Designated laboratories mostly adopt the gas chromatographic/mass spectrometric (GC/MS) technique for the identifi cation of CWAs and their degradation compounds.…”

A simple and economical chemical neutralization method for the destruction of sulfur mustard and its analogues

“…An international organization, known as Organization for Prohibition of Chemical Weapons (OPCW) is responsible for implementation of the treaty by executing its strict verification program. As per CWC, all the member states are obliged to essentially destroy stockpiles of Chemical warfare agents in irreversible manner before the year 2007 [1][2][3][4][5][6][7]. The chemicals relevant to the convention (CRCs) not only include the popular chemical warfare agents but precursors and degradation products are also included.…”

Mass spectral analysis of synthones of nerve agents for verification of the Chemical Weapons Convention

“…The analysis is performed either on-site by the inspectors or off-site by at least two designated laboratories appointed by the OPCW. [9][10][11][12][13][14] A laboratory can become and remain designated only by proving its analytical capability in official proficiency tests (PTs) conducted by the OPCW. 11,15 -18 The performance of participating laboratory in PTs mainly depends on availability of spectral data of CWC-related chemicals, sample preparation, analytical skills of chemists, judgment, and reporting.…”