In this article, I argue that we have moved into a new artistic, literary, social, media and economic period, wherein cyberculture reigns at the crossroads of real and virtual spaces and affects our literary and artistic productions, publication outlets, communication means and economic transactions. To show this, I elaborate on paradigms of cyberculturalism, including artificial intelligence, multimediality, omnipresence of social media, Twitterature, cybercommerce and cryptocurrency, in art, literature, culture and economics. I also discuss how the paradigms of cyberculturalism create new re-arrangements in the world and affect our perspectives, communications and transactions in post-postmodernity.