Characterisation of a group of endogenous gammaretroviruses in the canine genome

Tarlinton, Rachael; Barfoot, Hannah K.R.; Allen, Ceri E.; Brown, Katherine A.; Gifford, Robert J.; Emes, Richard D.

doi:10.1016/j.tvjl.2012.08.011

Cited by 17 publications

(16 citation statements)

References 24 publications

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“…Terrestrial boreoeutherians, marsupials, and birds Marine and terrestrial boreoeutherians, marsupials, birds, reptiles, and amphibians (Anai et al, 2012;Bamunusinghe et al, 2013;Bolisetty et al, 2012;Elleder et al, 2012;Fiebig et al, 2006;Hanger et al, 2000;Jaratlerdsiri et al, 2009;Lamere et al, 2009;Martin et al, 1999;Patience et al, 2001;Tarlinton et al, 2013;Tristem et al, 1996;Wang et al, (Bertsch et al, 2009;Gayral et al, 2008;Iskra-Caruana et al, 2010;Kunii et al, 2004;Staginnus and Richert-Pöggeler, 2006) Furthermore, there is also a tendency for non-agriculturally and medically important viruses to be overlooked. As a result, it could thus be that the actual viral host range is much broader than surveillance of existing viruses alone could reveal.…”

Section: Boreoeutheriansmentioning

confidence: 99%

Endogenous viruses: Connecting recent and ancient viral evolution

2015

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The rapid rates of viral evolution allow us to reconstruct the recent history of viruses in great detail. This feature, however, also results in rapid erosion of evolutionary signal within viral molecular data, impeding studies of their deep history. Thus, the further back in time, the less accurate the inference becomes. Furthermore, reconstructing complex histories of transmission can be challenging, especially where extinct viral lineages are concerned. This problem has been partially solved by the discovery of viruses embedded in host genomes, known as endogenous viral elements (EVEs). Some of these endogenous viruses are derived from ancient relatives of extant viruses, allowing us to better examine ancient viral host range, geographical distribution and transmission routes. Moreover, our knowledge of viral evolutionary timescales and rate dynamics has also been greatly improved by their discovery, thereby bridging the gap between recent and ancient viral evolution.

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Section: Boreoeutheriansmentioning

confidence: 99%

Endogenous viruses: Connecting recent and ancient viral evolution

2015

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“…The elements from Class I clustered into 17 subgroups (CfERV γ1 to γ17), while the elements from Class II clustered into 7 groups (CfERV β1 to β7) [32]. However, some concerns have been raised regarding this classification [33]. Their insertion could have occurred between 2.35-25.63 MYA according to conservative estimates, or, if the criteria were relaxed, it could have occurred between 0.83-42.97 MYA [32].…”

Section: Presence Of Ervs In Domestic Animalsmentioning

confidence: 99%

“…Seven canine ERVs were found in different breeds by RT-qPCR expression [33]. The expression of the pol gene of this group was detected in 8 organs (liver, kidney, mesenteric lymph node, lung, spleen, jejunum, brain and stomach), but variability among tissues was not detected [33].…”

Section: Expression Of Ervs In Domestic Animalsmentioning

confidence: 99%

“…The expression of the pol gene of this group was detected in 8 organs (liver, kidney, mesenteric lymph node, lung, spleen, jejunum, brain and stomach), but variability among tissues was not detected [33]. However, none of these ERVs seemed to be able to express a complete provirus [33]. …”

Section: Expression Of Ervs In Domestic Animalsmentioning

confidence: 99%

“…NA, not analyzed. a [58]; b [30]; c [33, 60]; d [60]; e [38]; f [45]; g [66]; h [54]; i [57]; j [54]. …”

Section: Tablementioning

confidence: 99%

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Endogenous Retroviruses in Domestic Animals

Garcia-Etxebarria

Sistiaga-Poveda

Jugo

2014

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Endogenous retroviruses (ERVs) are genomic elements that are present in a wide range of vertebrates. Although the study of ERVs has been carried out mainly in humans and model organisms, recently, domestic animals have become important, and some species have begun to be analyzed to gain further insight into ERVs. Due to the availability of complete genomes and the development of new computer tools, ERVs can now be analyzed from a genome-wide viewpoint. In addition, more experimental work is being carried out to analyze the distribution, expression and interplay of ERVs within a host genome. Cats, cattle, chicken, dogs, horses, pigs and sheep have been scrutinized in this manner, all of which are interesting species in health and economic terms. Furthermore, several studies have noted differences in the number of endogenous retroviruses and in the variability of these elements among different breeds, as well as their expression in different tissues and the effects of their locations, which, in some cases, are near genes. These findings suggest a complex, intriguing relationship between ERVs and host genomes. In this review, we summarize the most important in silico and experimental findings, discuss their implications and attempt to predict future directions for the study of these genomic elements.

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Genomic environment and digital expression of bovine endogenous retroviruses

Garcia-Etxebarria

Jugo

2014

Gene

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Characterisation of a group of endogenous gammaretroviruses in the canine genome

Cited by 17 publications

References 24 publications

Endogenous viruses: Connecting recent and ancient viral evolution

Endogenous viruses: Connecting recent and ancient viral evolution

Endogenous Retroviruses in Domestic Animals

Genomic environment and digital expression of bovine endogenous retroviruses

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