Characterisation of an antenna system implanted into a limb phantom for monitoring of bone fracture healing

Symeonidis, Symeon; Whittow, William G.; Wolfson, Chinthana Panagamuwa

doi:10.1109/lapc.2016.7807607

Cited by 5 publications

(3 citation statements)

References 21 publications

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“…For PCL it is possible to refer to [57]- [58] for its dielectric properties. The dielectric permittivity of the fracture gap was estimated employing the mixing model used in [59]. In fact, it is possible to discriminate between the ischemic and inflamed phase by weighing bone permittivity with blood Fig.…”

Section: B Simulation Parametersmentioning

confidence: 99%

Numerical Investigation of Bone Tumor Hyperthermia Treatment Using Magnetic Scaffolds

Fanti

Lodi

Vacca

et al. 2018

IEEE J. Electromagn. RF Microw. Med. Biol.

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This works claims to define, via numerical simulations, magnetic field parameters to perform an effective in situ bone tumor hyperthermia treatment using magnetic scaffolds. A Cole-Cole model to describe the frequency response of the magnetic susceptibility of nanoparticles embedded in novel magnetic biomaterials is explored. The heating phenomena is investigated considering both the ischemic and inflamed state of the fracture gap at the bone/implants interface. Both Osteosarcoma and Fibrosarcoma tumors are analyzed. Magnetic hydroxyapatite and poly-ε-caprolactone scaffolds are investigated. From the thermal analysis, it is found that the fracture behaves as a resistance to heat conduction, therefore strength and frequency of external magnetic field has to be tuned to perform the treatment taking the fracture status into account. Moreover, numerical experiments indicate that low perfused Fibrosarcoma can be treated using moderate-strength field, whereas more intense external fields are required to treat strongly vascularized Osteosarcoma without damaging healthy bone tissue. Magnetic hydroxyapatite stands out to be the most performant and versatile material to treat both tumors. These simulations can be regarded as a starting point to analyze possible clinical use of magnetic scaffolds for in situ bone hyperthermia.

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Section: B Simulation Parametersmentioning

confidence: 99%

Numerical Investigation of Bone Tumor Hyperthermia Treatment Using Magnetic Scaffolds

Fanti

Lodi

Vacca

et al. 2018

IEEE J. Electromagn. RF Microw. Med. Biol.

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show abstract

“…The process followed for producing the materials with equivalent dielectric properties to actual tissue, has been described in detail by the authors in [35][36][37][38]. For the measurements of the dielectric properties of phantom bone cortical, blood and muscle, an open-ended RG-402 semi-rigid coaxial cable-probe was used over the 0.5 to 4 GHz frequency range [39,40].…”

Section: Development Of Homogenous Tissue-mimicking Phantom Recipesmentioning

confidence: 99%

Bone fracture monitoring using implanted antennas in the radius, tibia and phalange heterogeneous bone phantoms

Symeonidis

Whittow

Panagamuwa

et al. 2018

Biomed. Phys. Eng. Express

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“…For the measurements of the dielectric parameters of each recipe, an open ended RG-402 semi-rigid coaxial cable -probe connected to an Anritsu MS46524A vector network analyzer that was calibrated over the 0.5 to 4 GHz frequency range was used. Detailed analysis on the operation principles of open ended probes for relative permittivity measurements of liquids can be found in [17]. An amount of 300ml of each measured material was put into a 350ml cylindrical plastic cup of 3.5cm radius.…”

Section: Characterising the Phantom Layersmentioning

confidence: 99%

Design and characterization of a three material anatomical bone phantom for implanted antenna applications

Symeonidis

Whittow

Panagamuwa

2017

Loughborough Antennas &Amp; Propagation Conference (LAPC 2017)

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This work presents the development and testing of a three layer anatomical human body phantom suitable for microwave applications. The proposed phantom consisted of bone marrow, bone cortical and muscle layers. The ingredients used for each tissue along with the calculation of the mean square error of the dielectric properties showed good agreement with the dielectric properties of real life tissues and the IEEE SAR measurement standard for tissue mimicking phantoms. The geometrical characteristics of the bone layer can be adjusted to fit the geometry of any desired bone in the human body. The suitability of the phantom has been tested using an implanted antennas application, which has yielded comparable simulation and measurement results.

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Characterisation of an antenna system implanted into a limb phantom for monitoring of bone fracture healing

Cited by 5 publications

References 21 publications

Numerical Investigation of Bone Tumor Hyperthermia Treatment Using Magnetic Scaffolds

Numerical Investigation of Bone Tumor Hyperthermia Treatment Using Magnetic Scaffolds

Bone fracture monitoring using implanted antennas in the radius, tibia and phalange heterogeneous bone phantoms

Design and characterization of a three material anatomical bone phantom for implanted antenna applications

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