Tuberculosis (TB) cases in Indonesia ranked second after India. According to Indonesia Health Profile, TB prevalence in 2016 was 351,893 cases and the number increased to 360,770 (2.5%) in 2017. Sintang regency is one of the regencies in Indonesia which is endemic for TB. Sintang had 272 TB cases in 2016 and it decreased to 161 in 2017. On the other hand, Kebong Health Center recorded that TB cases in children increased from 10 cases in 2016 to 40 in 2017. It meant that 24.84% of TB cases in Sintang occurred in children. The aim of this study was to determine the risk factors of TB in children incidence at Kebong HealthCenter. This study was analytic observational research with a case control design. The samples were 40 cases and 40 controls. The result showed that there was a significant relationship between knowledge (p value= 0,00; OR= 36,00) and incidence of TB occurring to children. There were no relationships between exclusive breastfeeding (p value = 0.666), economic status (p value = 0.329), occupancy density (p value = 0.421), room humidity (p value = 0.561) and room temperature (p value = 1,000) with TB incidence. It could be concluded that the parents' knowledge of TB was the risk factor of TB at Kebong Health Centre. Subsequently, the cases would increase 6 times higher if there was insufficient knowledge of TB in children.