Characteristic of clinical syndromes in patients with primary defects in antibody production

Abstract

Primary immunodeficiency is a rare disease with a high medico-social significance. Objective: to characterize principal clinical syndromes in 35 patients from 12 to 37 years old with primary immunodeficiency associated with an abnormal antibody production. The infectious syndrome is the most significant syndrome, it was revealed in all the patients, in some cases it was combined with autoimmune, atopic and lymphoproliferative syndrome. Thus, there isthe need to inform physicians of variousspecialties about this pathology. Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.