Characteristics and intermolecular interaction of eutectic binary mixtures: Reline and Glyceline

Abstract

Deep Eutectic Solvents are promising greener and cheaper alternatives to ionic liquids. The applications involving these solvents depend largely on their physical and chemical properties. However, a DES may possess both desirable and undesirable properties for a certain application. In such situations, mixing two DESs, each possessing a unique set of properties, may yield one with a more suitable set of physical and chemical properties for the same application. In this work, the variation in the physical properties of Reline upon addition of Glyceline was investigated. While a positive deviation of excess molar volume was observed, a negative deviation of viscosity was recorded with the increase in Glyceline mol% indicating a disruption of the ordered structure of Reline. The highest deviation in both cases was observed at 30 mol% Glyceline. The physical properties measured were density, viscosity, pH, RI and conductivity. The Glyceline molar percentage studied was 0 to 100 mol% while temperature was varied within the range of 20 o C to 80 o C.

Choline Chloride Based Deep Eutectic Solvents as a Tuneable Medium for Synthesis of Coumarinyl 1,2,4‐Triazoles: Effect of Solvent Type and Temperature

“…DESs formed between ChCl and urea is basic [41] and its low melting point indicates there are strong hydrogen bonds within the sol-vent, [42] while ChCl/N-methylurea DES is less basic. A proposed mechanism includes a nucleophilic attack of a nitrogen atom to carbon atom from the carbonyl group, which leads to the cyclization into 1,2,4-triazole ring.…”

“…It is evident that the basicity and the ability of the DES to form hydrogen bonds favors this cyclization. DESs formed between ChCl and urea is basic [41] and its low melting point indicates there are strong hydrogen bonds within the sol- vent, [42] while ChCl/N-methylurea DES is less basic. But when compared to ChCl/acetamide DES, which is basic, ChCl/N-methylurea DES possess much stronger hydrogen bonds, [42] obviously contributing to the formation of 1,2,4-triazole.…”

“…DESs are characterized as "green" solvents due to their non-toxicity, low vapor pressure, biodegradability, chemical stability, and environmentally benign effect. U r e a [33] 1: 2 80 TRI 3 Ethane-1,2-diol [41] 1: 2 40 TSC 4 Ethane-1,2-diol [43] 1:2 80 1.6:1 5 Combination of choline chloride with different HBDs affects DES' physical and chemical properties, like pH, viscosity, melting point, etc.…”

“…A screening was performed on a model reaction of 2-((4methyl-2-oxo-2H-chromen-7-yl)oxy)acetohydrazide (1) and phenyl isothiocyanate, followed by the synthesis of some triazole derivatives in the chosen DES and temperature. U r e a [33] 1 :2 80 TRI 3 Ethane-1,2-diol [41] 1: 2 40 TSC 4 Ethane-1,2-diol [43] 1:2 80 1.6:1 5…”

Influence of Hydration on the Structure and Interactions of Ethaline Deep‐Eutectic Solvent: A Spectroscopic and Computational Study

“…Despite the application potentials of DESs in variety of fields, finding a perfect DES with the exact favorable features is tough. One way to fine‐tune the properties of DESs to a specific application is through mixing them with other cosolvents . For instance, a limiting factor of DESs is their relatively high viscosities which have led to a great challenge in practical processing .…”