Characteristics and outcomes of out-of-hospital cardiac arrest in Zhejiang Province

Fei, Min; Cai, Wenwei; Zhou, Sheng-Ang

doi:10.5847/wjem.j.1920-8642.2018.02.010

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…Literature shows comparable non-conveyance rates for this age group. [21] Possible explanations might be that the Dutch national EMS protocol is more likely to advise to convey for younger children, that ambulance nurses are less willing to take risks with children and younger patients, or parental involvement during the conveyance decision-making process leading to higher conveyance rates. For all other age categories, non-conveyance rates are comparable, with the highest rate (15.3%) in the 50-59 years age group.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of non-conveyance ambulance runs: A retrospective study in the Netherlands

Ebben

Castelijns

Frenken

et al. 2019

World Journal of Emergency Medicine

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Section: Discussionmentioning

confidence: 99%

Characteristics of non-conveyance ambulance runs: A retrospective study in the Netherlands

Ebben

Castelijns

Frenken

et al. 2019

World Journal of Emergency Medicine

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“…However, the penetration rate of CPR training in China is not high, especially the resuscitation rate of out-of-hospital cardiac arrest is far lower than the international standard [4]. This is mainly due to inadequate CPR training and low public penetration [5]. College students have strong self-learning ability and thinking ability.…”

Section: Introductionmentioning

confidence: 99%

Application Effect of the China Association For Disaster and Emergency Rescue Medicine - Cardiopulmonary Resuscitation and Automatic Extracorporeal Defibrillation (CADERM-CPR·D) Training in Medical Teaching

Zhou,

Zhang,

Xie

et al. 2024

Cureus

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In China, the penetration rate of cardiopulmonary resuscitation training is not high and the effect of traditional teaching methods is not good. In this study, the case-guided cardiopulmonary resuscitation training mode was introduced to provide cardiopulmonary resuscitation training to medical students with a certain medical background, using the 2018 technical specifications for cardiopulmonary resuscitation and automatic extracorporeal defibrillation of the China Association for Disaster and Emergency Rescue Medicine. Compared with traditional teaching methods, the application effect of this training method in clinical probation teaching was analyzed. Methods120 medical students with a certain medical background were randomly divided into the experimental group and the control group, with 60 students in each group. The knowledge, skills, and attitude of the subjects were assessed by questionnaire survey. ResultsA total of 120 students were included in the study and randomly divided into an experimental group and a control group. The test scores of knowledge, skill, and attitude in the experimental group (38.40±2.775, 19.07±1.118, 14.92±0.962) were significantly higher than those in the control group (32.47±3.615, 14.65±1.338, 12.68±0.930)(P<0.05). ConclusionCase-guided cardiopulmonary resuscitation training of the China Association for Disaster and Emergency Rescue Medicine specifications can improve medical students' knowledge and skills of cardiopulmonary resuscitation, enhance their confidence in treatment, and can be further applied in medical teaching.

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Inhibition of microRNA-155 Alleviates Neurological Dysfunction Following Transient Global Ischemia and Contribution of Neuroinflammation and Oxidative Stress in the Hippocampus

Sun

Ji²,

Xing

2020

CPD

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Background/Aims: Central pro-inflammatory cytokine (PIC) signal is involved in neurological deficits after transient global ischemia induced by cardiac arrest (CA). The present study was to examine the role of microRNA- 155 (miR-155) in regulating IL-1β, IL-6 and TNF-α in the hippocampus of rats with induction of CA. We further examined the levels of products of oxidative stress 8-isoprostaglandin F2α (8-iso PGF2α, indication of oxidative stress); and 8-hydroxy-2’-deoxyguanosine (8-OHdG, indication of protein oxidation) after cerebral inhibition of miR-155. Methods: CA was induced by asphyxia and followed by cardiopulmonary resuscitation in rats. ELISA and western blot analysis were used to determine the levels of PICs and products of oxidative stress; and the protein expression of NADPH oxidase (NOXs) in the hippocampus. In addition, neurological severity score and brain edema were examined to assess neurological functions. Results: We observed amplification of IL-1β, IL-6 and TNF-α along with 8-iso PGF2α and 8-OHdG in the hippocampus of CA rats. Cerebral administration of miR-155 inhibitor diminished upregulation of PICs in the hippocampus. This also attenuated products of oxidative stress and upregulation of NOX4. Notably, inhibition of miR-155 improved neurological severity score and brain edema and this was linked to signal pathways of PIC and oxidative stress. Conclusion: We showed the significant role of blocking miR-155 signal in improving the neurological function in CA rats likely via inhibition of signal pathways of neuroinflammation and oxidative stress, suggesting that miR-155 may be a target in preventing and/or alleviating development of the impaired neurological functions during CA-evoked global cerebral ischemia.

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Characteristics and outcomes of out-of-hospital cardiac arrest in Zhejiang Province

Cited by 3 publications

References 10 publications

Characteristics of non-conveyance ambulance runs: A retrospective study in the Netherlands

Characteristics of non-conveyance ambulance runs: A retrospective study in the Netherlands

Application Effect of the China Association For Disaster and Emergency Rescue Medicine - Cardiopulmonary Resuscitation and Automatic Extracorporeal Defibrillation (CADERM-CPR·D) Training in Medical Teaching

Inhibition of microRNA-155 Alleviates Neurological Dysfunction Following Transient Global Ischemia and Contribution of Neuroinflammation and Oxidative Stress in the Hippocampus

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