Characteristics of Oil in Water (o/w) Type Lotions Incorporated with Kappa/Iota Carrageenan

Fransiska, Dina; Darmawan, Muhammad Arif; Sinurat, Ellya; Sedayu, Bakti Berlyanto; Wardhana, Yoga Windu; Herdiana, Yedi; Setiana, G P

doi:10.1088/1755-1315/715/1/012050

Cited by 7 publications

(6 citation statements)

References 4 publications

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“…The cosmetic industry uses principally synthetic or mineral dyes, some of which can cause allergies. Algae pigments (e.g., chlorophylls, carotenoids, and phycobiliproteins) may be a valid alternative [ 226 , 227 ]. The FDA has authorized spirulina extracts (containing phycobiliproteins) as colorants in human foods [ 228 , 229 ].…”

Section: Technological Properties Of the Algae Metabolitesmentioning

confidence: 99%

The Potential of Algae in the Nutricosmetic Sector

Dini

2023

Molecules

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Seaweeds or algae are marine autotrophic organisms. They produce nutrients (e.g., proteins, carbohydrates, etc.) essential for the survival of living organisms as they participate in biochemical processes and non-nutritive molecules (such as dietary fibers and secondary metabolites), which can improve their physiological functions. Seaweed polysaccharides, fatty acids, peptides, terpenoids, pigments, and polyphenols have biological properties that can be used to develop food supplements and nutricosmetic products as they can act as antibacterial, antiviral, antioxidant, and anti-inflammatory compounds. This review examines the (primary and secondary) metabolites produced by algae, the most recent evidence of their effect on human health conditions, with particular attention to what concerns the skin and hair’s well-being. It also evaluates the industrial potential of recovering these metabolites from biomass produced by algae used to clean wastewater. The results demonstrate that algae can be considered a natural source of bioactive molecules for well-being formulations. The primary and secondary metabolites’ upcycling can be an exciting opportunity to safeguard the planet (promoting a circular economy) and, at the same time, obtain low-cost bioactive molecules for the food, cosmetic, and pharmaceutical industries from low-cost, raw, and renewable materials. Today’s lack of methodologies for recovering bioactive molecules in large-scale processes limits practical realization.

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Section: Technological Properties Of the Algae Metabolitesmentioning

confidence: 99%

The Potential of Algae in the Nutricosmetic Sector

Dini

2023

Molecules

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“…Consumers are increasingly interested in using natural‐based cosmetics, a preference that coincides with the election of plant‐derived raw materials, including seaweed and its extracts. [177]. These sources have high hydrophilicity, mechanical strength, biocompatibility and biodegradability, so they are excellent materials for many formulations [23].…”

Section: Carrageenanmentioning

confidence: 99%

Trends in biopolymer science applied to cosmetics

Mendoza‐Muñoz

Leyva-Gómez

Piñón-Segundo

et al. 2023

Intern J of Cosmetic Sci

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The term biopolymer refers to materials obtained by chemically modifying natural biological substances or producing them through biotechnological processes. They are biodegradable, biocompatible and non‐toxic. Due to these advantages, biopolymers have wide applications in conventional cosmetics and new trends and have emerged as essential ingredients that function as rheological modifiers, emulsifiers, film‐formers, moisturizers, hydrators, antimicrobials and, more recently, materials with metabolic activity on skin. Developing approaches that exploit these features is a challenge for formulating skin, hair and oral care products and dermatological formulations. This article presents an overview of the use of the principal biopolymers used in cosmetic formulations and describes their sources, recently derived structures, novel applications and safety aspects of the use of these molecules.

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“…A range of concentration was selected since there was no standard concentration for carrageenan in cosmetic preparation or cancer treatment to date. Since there were findings that recommended a ratio of 0.1-1.5% of carrageenan based on its isomer in a skincare formulation (Aria, 2021;Fransiska et al, 2021), it is crucial to test for its toxicity and effect from a low to higher concentration range.…”

Section: A Cytotoxicity Of Carrageenans and α-Tocopherol On A431ns Cellsmentioning

confidence: 99%

Antiproliferative Effect of Carrageenans on Epidermoid Carcinoma (A431NS) Cells Through Inhibition of DNA Synthesis and Translationally- Controlled Tumour Protein (TPT1) Gene Expression

Thevanayagam¹,

Mohamed²,

Chu³

et al. 2023

ASMScJ

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Carrageenans are polysaccharide constituents of red seaweed cell walls used in food and medicine as well as thickening agents and excipients in cosmetics and skincare products. Carrageenans have antioxidants, anti-inflammatory and pro-apoptotic properties that could potentially cause antiproliferative effects against cancer cells. The primary aim of this study was to assess the antiproliferative effect of iota (ι) and kappa (κ)-carrageenan as well as their combination with α-tocopherol on epidermoid carcinoma (A431NS) cells concerning DNA synthesis and translationally-controlled tumour protein (TPT1) gene expression. Carrageenans exhibited cytotoxic effects against A431NS cells with CD50<100ug/ml and an antiproliferative effect in a concentration-dependent manner after 24, 48 and 72 hours of treatment by inhibiting DNA synthesis in these cells. The expression of the TPT1 gene increased significantly (p<0.05) in untreated A431NS cells. However, the expression was either lowered or completely suppressed in groups treated with carrageenans and/or α-tocopherol compared to the untreated cells. This study indicates that carrageenans can exhibit an antiproliferative effect via inhibition of DNA synthesis and downregulation of TPT1 gene expression in A431NS cells. The anticancer activity of carrageenans deserves further studies to explore their potential applications as an ingredient in cosmetics or skin care products for the prevention of skin cancer.

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Characteristics of Oil in Water (o/w) Type Lotions Incorporated with Kappa/Iota Carrageenan

Cited by 7 publications

References 4 publications

The Potential of Algae in the Nutricosmetic Sector

The Potential of Algae in the Nutricosmetic Sector

Trends in biopolymer science applied to cosmetics

Antiproliferative Effect of Carrageenans on Epidermoid Carcinoma (A431NS) Cells Through Inhibition of DNA Synthesis and Translationally- Controlled Tumour Protein (TPT1) Gene Expression

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