Characteristics of pertussis outbreaks in Catalonia, Spain, 1997 to 2010

Crespo, Inma; Broner, Sònia; Soldevila, Núria; Martı́nez, Ana; Godoy, Pere; Sala-Farré, Maria-Rosa; Rius, Cristina; Domı́nguez, Àngela

doi:10.4161/hv.36156

Cited by 8 publications

(5 citation statements)

References 23 publications

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“…Regarding pertussis, prior studies have also revealed a marked age distribution in cases, with the highest incidence among the youngest [ 29 , 30 ]. Although the incidence is not reported in our study, 89.7% of PC visits and 100% of referrals to specialists were recorded in the population < 45 years of age, which serves as an indicator of a greater number of cases in this group.…”

Section: Discussionmentioning

confidence: 99%

Direct Medical Costs of Four Vaccine-Preventable Infectious Diseases in Older Adults in Spain

Miguel

Bouza

Alcorta

et al. 2022

PharmacoEconomics Open

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Section: Discussionmentioning

confidence: 99%

Direct Medical Costs of Four Vaccine-Preventable Infectious Diseases in Older Adults in Spain

Miguel

Bouza

Alcorta

et al. 2022

PharmacoEconomics Open

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“…The authors recognise that this number is far below the reported and estimated data in other countries, and therefore assume severe underreporting based on the method of collecting surveillance data [41]. In the region of Catalonia, Spain, Crespo et al reported a similar incidence rate of 0.11 per 100,000 person-years for 1997-2010 in people >45 years of age [42]. Sizaire et al analysed the same data as Fernández-Cano [41], as well as additional data for 2010−2012.…”

Section: Europementioning

confidence: 95%

“…Sala-Farré et al reported no deaths among confirmed pertussis cases and most hospitalised cases were infants [41]. Crespo et al reported one death from 2004, but the age of the individual was not specified [42,49].…”

Section: Mortality and Morbiditymentioning

confidence: 99%

The burden of pertussis in older adults: what is the role of vaccination? A systematic literature review

Kandeil

Atanasov²,

Avramioti³

et al. 2019

Expert Review of Vaccines

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Introduction: Pertussis (whooping cough) is a vaccine-preventable disease; however, neither naturalnor vaccine-induced protection is lifelong. Although generally not severe in adults, pertussis can be associated with complications in patients with chronic conditions such as asthma or chronic obstructive pulmonary disease, and can be readily transmitted to more vulnerable populations, including neonates before they complete their primary vaccination. Furthermore, as the global population ages, the health and economic burden of the disease is expected to rise. Areas covered: A systematic literature review was conducted to ascertain the current epidemiological and financial burden of pertussis in older adults and to discuss the potential value of a booster vaccination in this population. Expert commentary: Our review indicates a considerable underestimation of the pertussis burden amongst older adults. Seroprevalence studies consistently demonstrate that the reported incidence may be much lower than the actual incidence. Tetanus toxoid-reduced diphtheria toxoid and acellular pertussis vaccines are immunogenic in older adults, induce high booster responses and are welltolerated. There is therefore a good rationale for the advocacy of booster pertussis vaccination throughout life to prevent pertussis infection and its transmission, especially in adults aged ≥50 years.

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“…In contrast, few data are available from Latin American, Asian, and African countries compared with Europe and the United States (174,(439)(440)(441)(442)(443)(444)(445)(446). In the United States, reported outbreaks that have been investigated by local and state health departments have affected diverse populations, including school children, military personnel, and hospitalized patients (245,(446)(447)(448)(449)(450)(451)(452)(453). During the past decade, several pertussis outbreaks have been associated with pockets of underimmunization of children (454)(455)(456).…”

Section: Control Measures For Pertussis Outbreaksmentioning

confidence: 99%

Pertussis: Microbiology, Disease, Treatment, and Prevention

et al. 2016

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SUMMARYPertussis is a severe respiratory infection caused byBordetella pertussis, and in 2008, pertussis was associated with an estimated 16 million cases and 195,000 deaths globally. Sizeable outbreaks of pertussis have been reported over the past 5 years, and disease reemergence has been the focus of international attention to develop a deeper understanding of pathogen virulence and genetic evolution ofB. pertussisstrains. During the past 20 years, the scientific community has recognized pertussis among adults as well as infants and children. Increased recognition that older children and adolescents are at risk for disease and may transmitB. pertussisto younger siblings has underscored the need to better understand the role of innate, humoral, and cell-mediated immunity, including the role of waning immunity. Although recognition of adult pertussis has increased in tandem with a better understanding ofB. pertussispathogenesis, pertussis in neonates and adults can manifest with atypical clinical presentations. Such disease patterns make pertussis recognition difficult and lead to delays in treatment. Ongoing research using newer tools for molecular analysis holds promise for improved understanding of pertussis epidemiology, bacterial pathogenesis, bioinformatics, and immunology. Together, these advances provide a foundation for the development of new-generation diagnostics, therapeutics, and vaccines.

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Characteristics of pertussis outbreaks in Catalonia, Spain, 1997 to 2010

Cited by 8 publications

References 23 publications

Direct Medical Costs of Four Vaccine-Preventable Infectious Diseases in Older Adults in Spain

Direct Medical Costs of Four Vaccine-Preventable Infectious Diseases in Older Adults in Spain

The burden of pertussis in older adults: what is the role of vaccination? A systematic literature review

Pertussis: Microbiology, Disease, Treatment, and Prevention

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