Characteristics of Pupil Offset in Young Asian Adults With Mild-Moderate and High Myopia

Sun, Shengshu; Liu, Zhanglin; Wu, Yuan; Sun, Xiaowen; Huang, Yue

doi:10.1167/tvst.11.6.13

Cited by 3 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found that pupil offset was linearly and positively correlated with preoperative MRSE in this study, which was consistent with a previous study (21). Furthermore, If the pupil offset was > 0.20 mm, there was a statistically signi cant correlation between pupil offset and MRSE.…”

Section: Discussionsupporting

confidence: 92%

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Liu

Zhao

Sun

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Background This study aimed to investigate the relationship between multiple higher-order aberrations (HOAs) subgroups and pupil offset, as well as to analyze the factors affecting postoperative corneal HOAs in patients with different degrees of refractive errors. Methods We enrolled 160 patients (316 eyes) aged ≥ 18 years who had undergone femtosecond laser-assisted in situ keratomileusis (FS-LASIK) treatment. Based on the relationship between the preoperative pupil offset and the postoperative ΔHOAs, all patients were divided into two groups: group I (pupil offset ≤ 0.20 mm) and group II (pupil offset > 0.20 mm). All of the eyes had low to high myopia with or without astigmatism (manifest refraction spherical equivalent (MRSE) < -10.00 D). Uncorrected distance visual acuity, corrected distance visual acuity, MRSE, pupil offset, central corneal thickness, corneal HOAs, vertical coma (Z3 − 1), horizontal coma (Z31), spherical aberration (Z40), trefoil 0° (Z33), and trefoil 30° (Z3 − 3) over a 6 mm diameter central corneal zone diameter were evaluated preoperatively and at 1 and 3 months postoperatively. Results Our result revealed significant differences in postoperative corneal total root mean square (RMS) HOAs, RMS vertical coma, RMS horizontal coma, RMS spherical aberration, and RMS trefoil 30° between group I and group Ⅱ. ΔMRSE was found to be an effective factor for ΔRMS HOAs (R2 = 0.383), ΔRMS horizontal coma (R2 = 0.205), and ΔRMS spherical aberration (R2 = 0.397). In group II, multiple linear regression analysis revealed a significant correlation between preoperative pupillary offset and Δtotal RMS HOAs (R2 = 0.461), ΔRMS horizontal coma (R2 = 0.040), and ΔRMS trefoil 30°(R2 = 0.089). The ΔRMS vertical coma effect factor is the Y-component, and the factor influencing ΔRMS spherical aberration was ΔMRSE (R2 = 0.256). Conclusion A small pupil offset was associated with a lower induction of postoperative corneal HOAs. Efforts to optimize centration are critical for improving surgical outcomes in patients with FS-LASIK.

show abstract

Section: Discussionsupporting

confidence: 92%

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Liu

Zhao

Sun

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

Effect of preoperative pupil offset on corneal higher-order aberrations after femtosecond laser-assisted in situ keratomileusis

et al. 2023

View full text Add to dashboard Cite

Background This study aimed to investigate the relationship between multiple higher-order aberrations (HOAs) subgroups and pupil offset, as well as to analyze the factors affecting postoperative corneal HOAs in patients with different degrees of refractive errors. Methods We enrolled 160 patients (316 eyes) aged ≥ 18 years who had undergone femtosecond laser-assisted in situ keratomileusis (FS-LASIK) treatment. Based on the relationship between the preoperative pupil offset and the postoperative ΔHOAs, all patients were divided into two groups: group I (pupil offset ≤ 0.20 mm) and group II (pupil offset > 0.20 mm). All of the eyes had low to high myopia with or without astigmatism (manifest refraction spherical equivalent (MRSE) < -10.00 D). Uncorrected distance visual acuity, corrected distance visual acuity, MRSE, pupil offset, central corneal thickness, corneal HOAs, vertical coma (Z3−1), horizontal coma (Z31), spherical aberration (Z40), trefoil 0° (Z33), and trefoil 30° (Z3−3) over a 6 mm diameter central corneal zone diameter were evaluated preoperatively and at 1 and 3 months postoperatively. Results Our result revealed significant differences in postoperative corneal total root mean square (RMS) HOAs, RMS vertical coma, RMS horizontal coma, RMS spherical aberration, and RMS trefoil 30° between group I and group II. ΔMRSE was found to be an effective factor for ΔRMS HOAs (R2 = 0.383), ΔRMS horizontal coma (R2 = 0.205), and ΔRMS spherical aberration (R2 = 0.397). In group II, multiple linear regression analysis revealed a significant correlation between preoperative pupillary offset and Δtotal RMS HOAs (R2 = 0.461), ΔRMS horizontal coma (R2 = 0.040), and ΔRMS trefoil 30°(R2 = 0.089). The ΔRMS vertical coma effect factor is the Y-component, and the factor influencing ΔRMS spherical aberration was ΔMRSE (R2 = 0.256). Conclusion A small pupil offset was associated with a lower induction of postoperative corneal HOAs. Efforts to optimize centration are critical for improving surgical outcomes in patients with FS-LASIK.

show abstract

Comparison of Scheimpflug tomography, Placido disc, and combined Placido Scheimpflug in the measurement of pupil offset in myopic population

Ning,

Zhang

2024

Front. Med.

View full text Add to dashboard Cite

IntroductionThis study aimed to compare the consistency of pupil offset measurements obtained using the Pentacam, Keratron Scout, and Sirius devices.MethodsThis retrospective cross-sectional study included 146 young myopic individuals (292 eyes) scheduled for refractive surgery at Dalian Third People’s Hospital between January 2023 and December 2023. Three devices were utilized to measure the chord mu of the pupil deviation along with the Cartesian distances of the X and Y coordinates (Px, Py) associated with the pupil offset. Repeated-measures analysis of variance was used to compare differences in pupil offset acquisition across various devices. Additionally, the intraclass correlation coefficient (ICC) and Bland–Altman plot were utilized to assess the consistency among the three devices.ResultsChord mu, measured using the Pentacam, Keratron Scout, and Sirius devices, were 0.18 ± 0.10, 0.21 ± 0.11, and 0.18 ± 0.11, respectively. The Px values were 0.00 ± 0.14, -0.02 ± 0.16, and -0.01 ± 0.13, respectively, while the Py values were 0.09 ± 0.13, 0.10 ± 0.15, and 0.10 ± 0.13. The ICCs for the three device measurements, chord mu, Px, and Py, were 0.817, 0.900, and 0.855, respectively. When comparing the three devices, the 95% limits of agreement (LoA) for mu and Px measured using the Sirius and Keratron Scout were the narrowest, ranging from −0.15 to 0.08 and −0.11 to 0.13, respectively. Additionally, the 95% LoA for Py measured using the Sirius and Pentacam was the narrowest, ranging from −0.13 to 0.15. The pupil centers in both eyes were predominantly located above the apex of the cornea.ConclusionSirius, Keratron Scout, and Pentacam have good consistency in pupil shift measurement in young myopic patients, and the three devices can be used as references in clinical practice.

show abstract

Characteristics of Pupil Offset in Young Asian Adults With Mild-Moderate and High Myopia

Cited by 3 publications

References 30 publications

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Effect of Preoperative Pupil Offset on Corneal Higher-Order Aberrations after Femtosecond Laser-Assisted In Situ Keratomileusis

Effect of preoperative pupil offset on corneal higher-order aberrations after femtosecond laser-assisted in situ keratomileusis

Comparison of Scheimpflug tomography, Placido disc, and combined Placido Scheimpflug in the measurement of pupil offset in myopic population

Contact Info

Product

Resources

About