Characteristics of severe acute respiratory infection-associated hospitalization in Yemen, 2014/15

Abstract

Yémen : caractéristiques des cas d'hospitalisation associés aux infections respiratoires aiguës sévères, 2014-2015RÉSUMÉ Cette étude présente les agents étiologiques, les données démographiques des patients, la saisonnalité et les pathologies sous-jacentes chez des patients hospitalisés en raison d'infections respiratoires aiguës sévères (IRAS) au Yémen. Nous avons réalisé une analyse descriptive rétrospective des données portant sur les IRAS et couvrant la période de janvier 2014 à décembre 2015. Des sécrétions rhinopharyngées ont été prélevées par écouvillonnage pour chaque patient afin d'être testées en laboratoire. Un total de 1 346 échantillons diagnostiques ont été testés, parmi lesquels 733 (54 %) se sont avérés positifs aux virus de la grippe. Les virus de la grippe A(H3N2) (5 %) et A(H1N1)pdm09 (3 %) étaient prédominants. Le virus respiratoire syncytial (VRS) a été observé principalement chez les enfants (41 %). Les sujets de sexe masculin étaient plus touchés (61 %) que les sujets de sexe féminin. L'âge médian était d'un an (intervalle : 0,5-94). La durée médiane d'hospitalisation était de 6 jours. Les maladies cardio-vasculaires chroniques constituaient la pathologie la plus fréquemment rapportée ; 67 % ne présentaient aucune pathologie sous-jacente établie. Les cas d'hospitalisation étaient généralement associés à des virus respiratoires, en particulier au VRS, à l'adénovirus et à la grippe.ABSTRACT This study aims to describe etiological agents, demographic details of patients, seasonality and underlying conditions among patients hospitalized due to viral severe acute respiratory infection (SARI) in Yemen. We carried out a retrospective descriptive analysis of data from January 2014 to December 2015. Nasopharyngeal swabs were taken from each patient for laboratory testing. A total of 1346 diagnostic specimens were tested, of which 733 (54%) were positive for influenza viruses. Influenza A(H3) and A(H1N1) pdm09 predominated. Respiratory syncytial virus (RSV) was reported predominantly among children (41%). Males (61%) were more affected than females. The median age was 1 year (range 0.5-94.0). The median length of hospitalization was 6 days. Chronic cardiovascular disease was the most commonly reported underlying condition, but 67% had no documented underlying disease. Respiratory viruses, particularly RSV, adenovirus and influenza, were commonly associated with hospitalization for SARI.

Severe Acute Respiratory Infections With Influenza and Noninfluenza Respiratory Viruses: Yemen, 2011-2016

“…This result was similar to previously reports in Yemen and Jordan. 10,12 About 50% of cases were males, a finding that is similar to what had been reported from Mediterranean region. 7…”

“…Few studies were carried out to describe the mortality after influenza epidemic, 8 estimate the proportion of influenza and noninfluenza viruses and mortality among SARI patients, 9 and to understand the clinical characteristics of SARI associated with most detected pathogens during 2014-2015. 10 Still, there is gap in the information related to the role of influenza and noninfluenza viruses in severe outcome of SARI and associated factors. This study aimed to determine the proportions of influenza and noninfluenza virus among SARI patients, and assess the severity of SARI and its associated factors in Yemen.…”

Epidemiology and outcome of influenza‐associated infections among hospitalized patients with acute respiratory infections, Egypt national surveillance system, 2016‐2019

“…Previous studies indicated that seasonal influenza infection is aggravated by existing chronic illness, with diabetes as the most frequently reported chronic condition among patients with severe influenza infection. 23 This necessitates the early detection and treatment with antivirals in those patients.…”

A Snapshot of Influenza Surveillance, Vaccine Recommendations, and Vaccine Access, Drivers, and Barriers in Selected Middle Eastern and North African Countries

“…[16][17][18] In the same issue of the EMHJ, influenza outbreak characterization from other regional countries such as Jordan, lebanon, Morocco, and yemen were also published. [21][22][23][24] This is a step forward in the Eastern Mediterranean region; however, to establish effective prevention policies, more data including the health and economic burden of influenza over several seasons in the regional countries is needed.…”