Characterization and biological activity of Pefloxacin–imidazole mixed ligands complexes

Soayed, Amina A.; Refaat, Heba M.; El-Din, Doaa A. Noor

doi:10.1016/j.ica.2014.05.020

Cited by 16 publications

(15 citation statements)

References 44 publications

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“… 20 - 23 Reports regarding several silver complexes have been developed recently to increase antibacterial activity of ligands or acquire new biological effects. 1 , 2 , 14 , 16 , 24 The particular coordination of antibacterial quinolones in metal complexes with one silver ion bridge and two silver ions bridge have been previously described. 12 …”

Section: Characterization Of Quinolone-metal Complexesmentioning

confidence: 99%

“…An excellent example for this is the antibacterial activity of metal complexes with quinolones. 1 , 2 Increased biological effect can be attributed to the interaction of metals with an active organic molecule, and also to the synergism of the antibacterial effect of the complex components. 3 , 4 The metal complexes with antibacterial quinolones were summarized in previously published reviews.…”

Section: Introductionmentioning

confidence: 99%

“… 15 , 16 However, most of the quinolones may be coordinated through N-heterocycle from 7 positions. 1 , 2 , 17 Physico-chemical properties, stability and biological effects of the complexes may vary according to coordination site of silver ion. 12 …”

Section: Introductionmentioning

confidence: 99%

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Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones

Rusu¹,

Hancu²,

Imre³

2018

Adv Pharm Bull

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To describe the chemical structure and characterize physico-chemical properties of organometallic complexes it is necessary to use a complex set of analysis methods. Thus, this review has been compiled as a relevant guide which includes the most commonly used methods of analysis in the study of silver complexes with antibacterial quinolones, compounds with promising biological potential. This selection of analysis methods puts on balance the obtained data and the accessibility of the experimental approach. The steps to follow in order to obtain reliable structural information about organometallic complexes of silver, particularly the silver complexes of antibacterial quinolones, are established and presented in the review.

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Section: Characterization Of Quinolone-metal Complexesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones

Rusu¹,

Hancu²,

Imre³

2018

Adv Pharm Bull

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“…Antifungal verification was explained in opposition to two species (Aspergillus flavus as well as Candida albicans). These compounds s under study were known [26].…”

Section: Metal Complexes Of Nicotinic Acid and Imidazole:-cu +2 Complmentioning

confidence: 99%

Cu AND Mn COMPLEXES OF NICOTINIC ACID AND IMIDAZOLE: A CURRENT REVIEW.

Khan¹,

Kanwal²,

Iqbal³

et al. 2017

IJAR

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“…Pefloxacin, [1-ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid], which contains a naphthyridine core, is a broad-spectrum FQ antibacterial agent. It shows excellent antibacterial activity against most gram-negative and gram-positive bacteria (Soayed, Refaat, & Noor El-Din, 2014). Clinically, it is widely used in the treatment of respiratory and urinary infections.…”

Section: Introductionmentioning

confidence: 99%

Development of an indirect enzyme-linked immunosorbent assay and lateral-flow test strips for pefloxacin and its analogues in chicken muscle samples

Mukunzi

Suryoprabowo

Song

et al. 2017

Food and Agricultural Immunology

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An anti-pefloxacin (PEF) monoclonal antibody (mAb), an indirect competitive enzyme-linked immunosorbent assay and lateral-flow test strip methods were developed to detect fluoroquinolone (FQ) residues in chicken muscle samples. Under optimised conditions, the anti-PEF mAb showed reasonable cross-reactivity with nine FQs with a limit of detection of 0.082 ng/mL assayed in 0.01 M phosphate buffered saline (PBS) solution. The intra-and interassay recoveries from spiked samples were within the range of 62.42-111.47% and 63.5-113.79%, respectively. The visual cut-off values of the lateral flow test strip in 0.01 M PBS and in food matrices were within the range of 2.5-50 ng/mL and 5-100 µg/kg, respectively. These results show that the anti-PEF mAb immunoassay and lateral flow test strip methods are suitable for simultaneous detection and routine monitoring of FQ residues in food. ARTICLE HISTORY

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Characterization and biological activity of Pefloxacin–imidazole mixed ligands complexes

Cited by 16 publications

References 44 publications

Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones

Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones

Cu AND Mn COMPLEXES OF NICOTINIC ACID AND IMIDAZOLE: A CURRENT REVIEW.

Development of an indirect enzyme-linked immunosorbent assay and lateral-flow test strips for pefloxacin and its analogues in chicken muscle samples

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